Prospecting for aptamers in the human genome

Philip C. Bevilacqua, Peter C. Breen, Pallavi Thaplyal

Research output: Contribution to journalShort surveypeer-review

Abstract

Aptamers are RNA molecules that bind small molecules. They were originally isolated from random libraries and then found in bacteria. In this issue of Chemistry & Biology, Vu et al. demonstrate that a motif for an adenosine aptamer occurs in human and bacterial genomes and binds AMP and ATP in vitro.

Original languageEnglish (US)
Pages (from-to)1218-1220
Number of pages3
JournalChemistry and Biology
Volume19
Issue number10
DOIs
StatePublished - Oct 26 2012

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmacology
  • Drug Discovery
  • Clinical Biochemistry

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