Prospecting for aptamers in the human genome

Philip C. Bevilacqua, Peter C. Breen, Pallavi Thaplyal

Research output: Contribution to journalShort survey

Abstract

Aptamers are RNA molecules that bind small molecules. They were originally isolated from random libraries and then found in bacteria. In this issue of Chemistry & Biology, Vu et al. demonstrate that a motif for an adenosine aptamer occurs in human and bacterial genomes and binds AMP and ATP in vitro.

Original languageEnglish (US)
Pages (from-to)1218-1220
Number of pages3
JournalChemistry and Biology
Volume19
Issue number10
DOIs
StatePublished - Oct 26 2012

Fingerprint

Nucleotide Aptamers
Bacterial Genomes
Human Genome
Adenosine Monophosphate
Adenosine
Libraries
Genes
Adenosine Triphosphate
Bacteria
Molecules
In Vitro Techniques

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmacology
  • Drug Discovery
  • Clinical Biochemistry

Cite this

Bevilacqua, Philip C. ; Breen, Peter C. ; Thaplyal, Pallavi. / Prospecting for aptamers in the human genome. In: Chemistry and Biology. 2012 ; Vol. 19, No. 10. pp. 1218-1220.
@article{f56a7f2eb591444c971b4d0f5b99aa28,
title = "Prospecting for aptamers in the human genome",
abstract = "Aptamers are RNA molecules that bind small molecules. They were originally isolated from random libraries and then found in bacteria. In this issue of Chemistry & Biology, Vu et al. demonstrate that a motif for an adenosine aptamer occurs in human and bacterial genomes and binds AMP and ATP in vitro.",
author = "Bevilacqua, {Philip C.} and Breen, {Peter C.} and Pallavi Thaplyal",
year = "2012",
month = "10",
day = "26",
doi = "10.1016/j.chembiol.2012.10.001",
language = "English (US)",
volume = "19",
pages = "1218--1220",
journal = "Cell Chemical Biology",
issn = "2451-9448",
publisher = "Elsevier Inc.",
number = "10",

}

Prospecting for aptamers in the human genome. / Bevilacqua, Philip C.; Breen, Peter C.; Thaplyal, Pallavi.

In: Chemistry and Biology, Vol. 19, No. 10, 26.10.2012, p. 1218-1220.

Research output: Contribution to journalShort survey

TY - JOUR

T1 - Prospecting for aptamers in the human genome

AU - Bevilacqua, Philip C.

AU - Breen, Peter C.

AU - Thaplyal, Pallavi

PY - 2012/10/26

Y1 - 2012/10/26

N2 - Aptamers are RNA molecules that bind small molecules. They were originally isolated from random libraries and then found in bacteria. In this issue of Chemistry & Biology, Vu et al. demonstrate that a motif for an adenosine aptamer occurs in human and bacterial genomes and binds AMP and ATP in vitro.

AB - Aptamers are RNA molecules that bind small molecules. They were originally isolated from random libraries and then found in bacteria. In this issue of Chemistry & Biology, Vu et al. demonstrate that a motif for an adenosine aptamer occurs in human and bacterial genomes and binds AMP and ATP in vitro.

UR - http://www.scopus.com/inward/record.url?scp=84868033529&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84868033529&partnerID=8YFLogxK

U2 - 10.1016/j.chembiol.2012.10.001

DO - 10.1016/j.chembiol.2012.10.001

M3 - Short survey

C2 - 23102215

AN - SCOPUS:84868033529

VL - 19

SP - 1218

EP - 1220

JO - Cell Chemical Biology

JF - Cell Chemical Biology

SN - 2451-9448

IS - 10

ER -