Prospective validation of a perinatal bacterial vaginosis screening risk score

Lisa M. Pastore, Tonya S. King, Ida J. Dawson, Alisa Hollifield, John M. Thorp

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Objective: Prospectively validate an antenatal bacterial vaginosis (BV) risk score at two public health department obstetrics clinics. Study Design: Women (n = 409) entering prenatal care received a BV risk score (range 0 to 16) at their first visit and at 24 to 28 weeks' gestation. BV was measured with Gram-stained vaginal smears. Normal discharge was used as a surrogate for being asymptomatic. Results: Approximately half of the women scored ≥3 at each assessment. In total 29% had true BV at the first assessment (13% at the second assessment). The BV risk score, (≥3) had 9% sensitivity and 63% specificity, and the BV risk score (≥5) had 88% sensitivity and 76% specificity. Among true cases, 42% were asymptomatic, of which 77% had risk scores ≥3. All symptomatic BV cases had risk scores ≥3. Conclusion: In practice, the risk score identified both asymptomatic and symptomatic cases. Asymptomatic women are of particular interest because they are not screened for BV under current practice guidelines.

Original languageEnglish (US)
Pages (from-to)735-742
Number of pages8
JournalJournal of Perinatology
Volume24
Issue number12
DOIs
StatePublished - Dec 2004

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

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