Prostaglandin levels in endometrial jet wash specimens in patients with dysmenorrhea before and after indomethacin therapy

David R. Halbert, Laurence Demers, John Fontana, D. E.Darnell Jones

Research output: Contribution to journalArticle

44 Citations (Scopus)

Abstract

A patient with functional primary dysmenorrhea of over two years duration was subjected to the endometrial jet wash technique during the period of active menstrual flow. Prostaglandin F analysis of the jet washings revealed significantly elevated levels during menstruation over normal control levels. Following indomethacin therapy, jet wash prostaglandin F levels were dramatically reduced and the patient became asymptomatic. A cause and effect relationship between prostaglandin F and dysmenorrhea is suggested by these studies.

Original languageEnglish (US)
Pages (from-to)1047-1056
Number of pages10
JournalProstaglandins
Volume10
Issue number6
DOIs
StatePublished - Jan 1 1975

Fingerprint

Dysmenorrhea
Prostaglandins F
Indomethacin
Prostaglandins
Menstruation
Level control
Washing
Therapeutics

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Endocrinology

Cite this

Halbert, David R. ; Demers, Laurence ; Fontana, John ; Jones, D. E.Darnell. / Prostaglandin levels in endometrial jet wash specimens in patients with dysmenorrhea before and after indomethacin therapy. In: Prostaglandins. 1975 ; Vol. 10, No. 6. pp. 1047-1056.
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Prostaglandin levels in endometrial jet wash specimens in patients with dysmenorrhea before and after indomethacin therapy. / Halbert, David R.; Demers, Laurence; Fontana, John; Jones, D. E.Darnell.

In: Prostaglandins, Vol. 10, No. 6, 01.01.1975, p. 1047-1056.

Research output: Contribution to journalArticle

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