Prostatic irradiation-induced sexual dysfunction: A review and multidisciplinary guide to management in the radical radiotherapy era (Part II on Urological Management)

Marc J. Rogers, Marigdalia K. Ramirez-Fort, James A. Kashanian, Seth A. Broster, Jaime Matta, Sean S. Mahase, Digna V. Fort, M. Junaid Niaz, Shearwood McClelland, Neil H. Bander, Migdalia Fort, Christopher S. Lange, Peter Schlegel, John P. Mulhall

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations

Abstract

Prostate cancer is the most common malignancy in men and the second leading cause of cancer-related death in men. Radiotherapy is a curative option that is administered via external beam radiation, brachytherapy, or in combination. Sexual dysfunction is a common toxicity following radiotherapy, similar to men undergoing radical prostatectomy, but the etiology is different. The pathophysiology of radiation-induced sexual dysfunction is multi-factorial, and the toxicity is a major cause of impaired quality of life among long-term prostate cancer survivors. Management of a patient's sexual function during and after radiotherapy requires multidisciplinary coordination of care between radiation oncology, urology, psychiatry, pharmacy, and dermatology. This review provides a framework for clinicians to better understand prostatic radiotherapy-induced sexual dysfunction diagnosis, evaluation, and a patient-centered approach to toxicity preventive strategies and management.

Original languageEnglish (US)
Pages (from-to)619-624
Number of pages6
JournalReports of Practical Oncology and Radiotherapy
Volume25
Issue number4
DOIs
StatePublished - Jul 1 2020

All Science Journal Classification (ASJC) codes

  • Oncology
  • Radiology Nuclear Medicine and imaging

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