Protracted analgesia in young and adult rats maternally exposed to methadone

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Abstract

The analgesic response to the hot-plate test was studied in 21-, 45-, 60-, 120- and 300-day-old rats maternally exposed to methadone (5 mg/kg). An elevation in nociceptive threshold, in the absence of further exposure to methadone, was observed in young and adult rats perinatally subjected to methadone.

Original languageEnglish (US)
Pages (from-to)329-330
Number of pages2
JournalExperientia
Volume36
Issue number3
DOIs
StatePublished - Mar 1 1980

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)

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