TY - JOUR
T1 - Psychological measures of patient’s decision-making for prenatal genetic testing
AU - Herrera, Kimberly M.
AU - Milone, Gina
AU - Davis, Jay A.
AU - Persad, Malini D.
AU - Dinglas, Cheryl
AU - Heiselman, Cassandra
AU - Buckley, Ayisha
AU - Garretto, Diana
AU - Pastore, Lisa M.
N1 - Funding Information:
We acknowledge Drs. Marci Lobel (Stony Brook University) and Lisa Rubin (New School for Social Research) for their work on the development of these instruments. We thank Giselle Gerardi MSN, RN, RNC-OB and Cecelia Avila MD, for translating the instruments into Spanish.
Publisher Copyright:
© 2020 Informa UK Limited, trading as Taylor & Francis Group.
PY - 2022
Y1 - 2022
N2 - Objective: To use a questionnaire to determine the levels of maternal decision-related distress, clarity of the pros and cons, and certainty when considering prenatal genetic diagnostic testing; and to assess the relationship between these constructs and patient characteristics. Method: Cross-sectional study. Voluntary, anonymous questionnaires distributed 2017–2019 to women referred for invasive prenatal genetic testing. Excluded: English or Spanish illiterate. Maternal characteristics were collected. Questions evaluated distress, decisional certainty, and decisional clarity on a 5-point Likert scale (range: 0 = low/uncertain/unclear to 4 = high/certain/clear). Analysis: non-parametric Kruskal–Wallis, correlation statistics, and ANOVA. Results: Forty-four female patients completed it. Most were married, white, Catholic, and multiparous. 58% had already made a testing decision. Patients expressed low distress levels (mean 1.18 ± 0.80) and expressed high decisional certainty (mean 3.28 ± 0.76) and clarity (mean 3.30 ± 0.99). Decisional certainty and clarity were positively correlated (r = 0.47, p <.01), whereas distress was negatively correlated with decisional certainty (r = −0.8136, p <.0005) and decisional clarity (r = −0.49, p =.007). No significant differences by religion or parity. Greater distress (p <.05) and less decisional clarity (p =.07) occurred between those still debating testing vs those who had decided. Conclusions: Higher maternal distress scores were associated with lower decisional certainty and decisional clarity in women considering prenatal genetic testing.
AB - Objective: To use a questionnaire to determine the levels of maternal decision-related distress, clarity of the pros and cons, and certainty when considering prenatal genetic diagnostic testing; and to assess the relationship between these constructs and patient characteristics. Method: Cross-sectional study. Voluntary, anonymous questionnaires distributed 2017–2019 to women referred for invasive prenatal genetic testing. Excluded: English or Spanish illiterate. Maternal characteristics were collected. Questions evaluated distress, decisional certainty, and decisional clarity on a 5-point Likert scale (range: 0 = low/uncertain/unclear to 4 = high/certain/clear). Analysis: non-parametric Kruskal–Wallis, correlation statistics, and ANOVA. Results: Forty-four female patients completed it. Most were married, white, Catholic, and multiparous. 58% had already made a testing decision. Patients expressed low distress levels (mean 1.18 ± 0.80) and expressed high decisional certainty (mean 3.28 ± 0.76) and clarity (mean 3.30 ± 0.99). Decisional certainty and clarity were positively correlated (r = 0.47, p <.01), whereas distress was negatively correlated with decisional certainty (r = −0.8136, p <.0005) and decisional clarity (r = −0.49, p =.007). No significant differences by religion or parity. Greater distress (p <.05) and less decisional clarity (p =.07) occurred between those still debating testing vs those who had decided. Conclusions: Higher maternal distress scores were associated with lower decisional certainty and decisional clarity in women considering prenatal genetic testing.
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U2 - 10.1080/14767058.2020.1847074
DO - 10.1080/14767058.2020.1847074
M3 - Article
C2 - 33207999
AN - SCOPUS:85096296295
SN - 1476-7058
VL - 35
SP - 4130
EP - 4136
JO - Journal of Maternal-Fetal and Neonatal Medicine
JF - Journal of Maternal-Fetal and Neonatal Medicine
IS - 21
ER -