Puberty in boys: Correlation of plasma levels of gonadotropins (lh, fsh), androgens (testosterone, androstenedione, dehydroepiandrosterone and its sulfate), estrogens (estrone and estradiol) and progestins (progesterone and 17-hydroxyprogesterone)

Peter A. Lee, Claude J. Migeon

Research output: Contribution to journalArticle

87 Scopus citations

Abstract

Mean serum concentration of dehydroepiandrosterone (DHA), DHA 'sulfate (DHAS), progesterone (P), 17-hydroxyprogesterone (17-OH-P), estrone (E1, estradiol (E2), and androstenedione (A) were compared from 43.boys followed longitudinally for as long as 4 yr during puberty. These data were also compared with serum levels of LH, FSH, and testosterone. Elevation is recognized early in.puberty for DHAS, late in puberty for P and A, and gradually throughout puberty for E, 17-OH-P, and DHA. When compared by age, the same general pattern is apparent with adult levels of E1 reached at age 12, DHAS and E2 by 13, and DHA, P, 17-OH-P, and A not until after age 15. Significant elevations of DHA occurred with the onset of pubic hair and voice change; elevations of DHAS occurred with the onset of genital and axillary hair growth; and testosterone increased with the onset of genital and pubic hair growth and voice change.

Original languageEnglish (US)
Pages (from-to)556-562
Number of pages7
JournalJournal of Clinical Endocrinology and Metabolism
Volume41
Issue number3
DOIs
StatePublished - Sep 1975

All Science Journal Classification (ASJC) codes

  • Endocrinology, Diabetes and Metabolism
  • Biochemistry
  • Endocrinology
  • Clinical Biochemistry
  • Biochemistry, medical

Fingerprint Dive into the research topics of 'Puberty in boys: Correlation of plasma levels of gonadotropins (lh, fsh), androgens (testosterone, androstenedione, dehydroepiandrosterone and its sulfate), estrogens (estrone and estradiol) and progestins (progesterone and 17-hydroxyprogesterone)'. Together they form a unique fingerprint.

  • Cite this