Extracorporeal membrane oxygenation (ECMO) is used to treat neonatal respiratory failure unresponsive to maximal conventional therapy. ECMO provides a period of 'lung rest' during which lung recovery occurs. Since the underlying pathophysiology of repiratory failure involves inadequate exchange of oxygen and carbon dioxide by the injured lung, quantitation of pulmonary gas exchange is the absolute measure of recovery. We have used a closed-circuit spirometry system to measure simultaneous oxygen consumption (V̇O2) and carbon dioxide production (V̇CO2) by the membrane lung (MemL) and native lung (NatL) during neonatal ECMO.
|Original language||English (US)|
|Number of pages||3|
|Publication status||Published - Jan 1 1985|
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