Pulse lavage is inadequate at removal of biofilm from the surface of total knee arthroplasty materials

Kenneth L. Urish, Peter W. DeMuth, David Craft, Hani Haider, Charles Davis

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

In acute periprosthetic infection, irrigation and debridement with component retention has a high failure rate in some studies. We hypothesize that pulse lavage irrigation is ineffective at removing biofilm from total knee arthroplasty (TKA) components. Staphylococcus aureus biofilm mass and location was directly visualized on arthroplasty materials with a photon collection camera and laser scanning confocal microscopy. There was a substantial reduction in biofilm signal intensity, but the reduction was less than a ten-fold decrease. This suggests that irrigation needs to be further improved for the removal of biofilm mass below the necessary bioburden level to prevent recurrence of acute infection in total knee arthroplasty.

Original languageEnglish (US)
Pages (from-to)1128-1132
Number of pages5
JournalJournal of Arthroplasty
Volume29
Issue number6
DOIs
StatePublished - Jan 1 2014

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Knee Replacement Arthroplasties
Therapeutic Irrigation
Biofilms
Debridement
Infection
Photons
Confocal Microscopy
Arthroplasty
Staphylococcus aureus
Recurrence

All Science Journal Classification (ASJC) codes

  • Orthopedics and Sports Medicine

Cite this

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Pulse lavage is inadequate at removal of biofilm from the surface of total knee arthroplasty materials. / Urish, Kenneth L.; DeMuth, Peter W.; Craft, David; Haider, Hani; Davis, Charles.

In: Journal of Arthroplasty, Vol. 29, No. 6, 01.01.2014, p. 1128-1132.

Research output: Contribution to journalArticle

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