Pyrethroid resistance in mosquitoes

Nannan Liu, Qiang Xu, Fang Zhu, Lee Zhang

Research output: Contribution to journalArticle

67 Citations (Scopus)

Abstract

Repeated blood feedings throughout their life span have made mosquitoes ideal transmitters of a wide variety of disease agents. Vector control is a very important part of the current global strategy for the control of mosquito-associated diseases and insecticide application is the most important component in this effort. Pyrethroids, which account for 25% of the world insecticide market, are currently the most widely used insecticides for the indoor control of mosquitoes and are the only chemical recommended for the treatment of mosquito nets, the main tool for preventing malaria in Africa. However, mosquito-borne diseases are now resurgent, largely because of insecticide resistance that has developed in mosquito vectors and the anti-parasite drug resistance of parasites. This paper reviews our current knowledge of the molecular mechanisms governing metabolic detoxification and the development of target site insensitivity that leads to pyrethroid resistance in mosquitoes.

Original languageEnglish (US)
Pages (from-to)159-166
Number of pages8
JournalInsect Science
Volume13
Issue number3
DOIs
StatePublished - Jun 2006

Fingerprint

Pyrethrins
pyrethroid
Insecticides
pyrethrins
Culicidae
mosquito
Mosquito Control
mosquito control
Parasites
insecticides
Mosquito Nets
insecticide
metabolic detoxification
mosquito nets
mosquito-borne diseases
Insecticide Resistance
parasites
vector control
insecticide resistance
drug resistance

All Science Journal Classification (ASJC) codes

  • Ecology, Evolution, Behavior and Systematics
  • Agronomy and Crop Science
  • Biochemistry, Genetics and Molecular Biology(all)
  • Insect Science

Cite this

Liu, Nannan ; Xu, Qiang ; Zhu, Fang ; Zhang, Lee. / Pyrethroid resistance in mosquitoes. In: Insect Science. 2006 ; Vol. 13, No. 3. pp. 159-166.
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Pyrethroid resistance in mosquitoes. / Liu, Nannan; Xu, Qiang; Zhu, Fang; Zhang, Lee.

In: Insect Science, Vol. 13, No. 3, 06.2006, p. 159-166.

Research output: Contribution to journalArticle

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