Quality of life, body mass index, and physical activity among uterine cancer patients

Lilie L. Lin, Justin C. Brown, Saya Segal, Kathryn H. Schmitz

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Objective: The purpose of this study was to assess the independent and joint effects of body mass index (BMI) and physical activity (PA) on overall quality of life (QoL) in survivors of uterine cancer. Methods: We conducted a survey among uterine cancer patients who received curative therapy at the University of Pennsylvania between 2006 and 2010. Surveys assessed the weight, height, PA (college alumnus survey), and QoL (Functional Assessment of Cancer TherapyYGynecologic Oncology Group). Results: The response rate to the survey was 43%. Among 213 patients, the mean (SD) BMI was 31.1 (8.9) kg/m2, and 48% reported greater than or equal to 150 minIwkj1 of PA. Higher BMI was independently associated with poorer overall QoL (P = 0.050), including physical (P = 0.002) and functional well-being (P = 0.008). Higher minIwkj1 of PAwas not independently associated with any QoL outcome. However, among patients who engaged in greater than or equal to 150 minIwkj1 of PA, the negative association between BMI and overall QoL was attenuated (P = 0.558), whereas among patients who engaged in less than 150 minIwkj1 of PA, the negative association between BMI and overall QoL persisted (P = 0.025). Among patients who engaged in greater than or equal to 150 minIwkj1 of PA, the negative association between BMI and physical and functional well-being was attenuated (P = 0.765 and P = 0.284), whereas among patients who engaged in less than 150 minIwkj1 of PA, the negative association between BMI and physical and functional well-being persisted (P < 0.001 and P = 0.010), respectively. Conclusions: Body mass index is associated with poorer QoL among uterine cancer patients. The findings from this cross-sectional study are consistent with the hypothesis that endometrial cancer survivors who are able to perform 150 min/wk of PA may be protected from the negative effects of BMI on QoL.

Original languageEnglish (US)
Pages (from-to)1027-1032
Number of pages6
JournalInternational Journal of Gynecological Cancer
Volume24
Issue number6
DOIs
StatePublished - Jul 2014

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Uterine Neoplasms
Body Mass Index
Quality of Life
Exercise
Survivors
Endometrial Neoplasms
Cross-Sectional Studies
Weights and Measures
Surveys and Questionnaires

All Science Journal Classification (ASJC) codes

  • Oncology
  • Obstetrics and Gynecology

Cite this

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title = "Quality of life, body mass index, and physical activity among uterine cancer patients",
abstract = "Objective: The purpose of this study was to assess the independent and joint effects of body mass index (BMI) and physical activity (PA) on overall quality of life (QoL) in survivors of uterine cancer. Methods: We conducted a survey among uterine cancer patients who received curative therapy at the University of Pennsylvania between 2006 and 2010. Surveys assessed the weight, height, PA (college alumnus survey), and QoL (Functional Assessment of Cancer TherapyYGynecologic Oncology Group). Results: The response rate to the survey was 43{\%}. Among 213 patients, the mean (SD) BMI was 31.1 (8.9) kg/m2, and 48{\%} reported greater than or equal to 150 minIwkj1 of PA. Higher BMI was independently associated with poorer overall QoL (P = 0.050), including physical (P = 0.002) and functional well-being (P = 0.008). Higher minIwkj1 of PAwas not independently associated with any QoL outcome. However, among patients who engaged in greater than or equal to 150 minIwkj1 of PA, the negative association between BMI and overall QoL was attenuated (P = 0.558), whereas among patients who engaged in less than 150 minIwkj1 of PA, the negative association between BMI and overall QoL persisted (P = 0.025). Among patients who engaged in greater than or equal to 150 minIwkj1 of PA, the negative association between BMI and physical and functional well-being was attenuated (P = 0.765 and P = 0.284), whereas among patients who engaged in less than 150 minIwkj1 of PA, the negative association between BMI and physical and functional well-being persisted (P < 0.001 and P = 0.010), respectively. Conclusions: Body mass index is associated with poorer QoL among uterine cancer patients. The findings from this cross-sectional study are consistent with the hypothesis that endometrial cancer survivors who are able to perform 150 min/wk of PA may be protected from the negative effects of BMI on QoL.",
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Quality of life, body mass index, and physical activity among uterine cancer patients. / Lin, Lilie L.; Brown, Justin C.; Segal, Saya; Schmitz, Kathryn H.

In: International Journal of Gynecological Cancer, Vol. 24, No. 6, 07.2014, p. 1027-1032.

Research output: Contribution to journalArticle

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