Quantitative measurement of neurologic impairment in patients with multiple sclerosis

Horst R. Konrad, David Good, Allen B. Devleschoward

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Eleven patients with clinically diagnosed multiple sclerosis were simultaneously evaluated with history, physical, and neurologic evaluations and a series of objective neurophysiology tests. Patients were then scored independently on clinical stage of their disease using a system based on symptoms in history or findings on physical or neurologic examination. Test scores on objective tests were compared with clinical scores with each evaluator. Patients with high test scores on clinical evaluation usually had high test scores on objective testing. Symptoms and physical findings were then correlated with abnormalities on objective tests. Objective abnormalities in visual evoked response and auditory evoked response on several occasions preceded the development of symptoms. All patients except for two had more than one abnormality on objective testing, suggesting a high likelihood that objective tests are helpful in the diagnosis of early-stage multiple sclerosis.

Original languageEnglish (US)
Pages (from-to)687-690
Number of pages4
JournalOtolaryngology-Head and Neck Surgery
Volume90
Issue number6
DOIs
StatePublished - Jan 1 1982

Fingerprint

Nervous System
Multiple Sclerosis
History
Auditory Evoked Potentials
Neurophysiology
Visual Evoked Potentials
Neurologic Examination
Physical Examination

All Science Journal Classification (ASJC) codes

  • Otorhinolaryngology
  • Surgery

Cite this

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Quantitative measurement of neurologic impairment in patients with multiple sclerosis. / Konrad, Horst R.; Good, David; Devleschoward, Allen B.

In: Otolaryngology-Head and Neck Surgery, Vol. 90, No. 6, 01.01.1982, p. 687-690.

Research output: Contribution to journalArticle

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