Quick assessment of cytotoxins effect on daphnia magna using in vivo fluorescence microscopy

Vera V. Teplova, Zhanna I. Andreeva-Kovalevskaya, Elena V. Sineva, Alexander S. Solonin

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

A novel approach to contaminant toxicity screening is proposed. The use of fluorescent microscopy with fluorescent dyes allows for assessing intoxication of Daphnia magna tissues, at various stages of exposure, to contaminants present in water. As shown, D. magna may not only be used as a test species in toxicity tests based on its lethality, but due to its translucency and application of fluorescent probes, separate steps of its intoxication and dying can be visualized. Using a variety of fluorescent probes, the present study also contributes to a better understanding of the toxicity mechanisms. Environ. Toxicol. Chem. 2010;29:1345-1348.

Original languageEnglish (US)
Pages (from-to)1345-1348
Number of pages4
JournalEnvironmental Toxicology and Chemistry
Volume29
Issue number6
DOIs
StatePublished - Jun 1 2010

All Science Journal Classification (ASJC) codes

  • Environmental Chemistry
  • Health, Toxicology and Mutagenesis

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