Radial artery spasm associated with transradial cardiovascular procedures: Results from the RAS registry

Alejandro Goldsmit, Ferdinand Kiemeneij, Ian C. Gilchrist, Pablo Kantor, Sasko Kedev, Tak Kwan, Surya Dharma, Leon Valdivieso, Bernard Wenstemberg, Tejas Patel

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49 Scopus citations


Objectives To report the incidence and predictors of moderate/severe radial artery spasm (RAS) in patients undergoing cardiovascular percutaneous procedures through a transradial approach (TRA) in centers with TRA expertise. Background Data regarding the actual rate of clinically meaningful RAS are limited due to difference in study designs and operator expertise. Methods The RAS registry, an international (14 centers from Argentina, Chile, India, Indonesia, Macedonia, The Netherlands and United States of America) registry that included 1,868 patients undergoing TRA cardiovascular procedures (63.5% diagnostic and 56.5% therapeutic).All selected centers used TRA as default strategy in the cardiac catheterization laboratory. Throughout 2012, each center included all consecutive TRA cases (during a 2-month period) into a dedicated database covering clinical characteristics as well as procedural topics related to TRA patterns and RAS occurrence. Results The incidence of moderate/severe RAS was 2.7%. Only 0.7% of patients required crossover (8 to transfemoral and 5 to contralateral TRA). Patients with moderately/severe spasm were more frequently females, had a history of dyslipidemia, received more often a 7F sheath and more puncture attempts than patients without spasm. By multivariate analysis, the need for more than one attempt and the use of a 7 F sheath were independent predictors of the development of moderate/severe RAS. Conclusions The incidence of moderate/severe RAS is low in centers with a default TRA. Its development appears to be strongly related to the numbers of puncture attempts and the use of large sheaths. © 2013 Wiley Periodicals, Inc.

Original languageEnglish (US)
Pages (from-to)E32-E36
JournalCatheterization and Cardiovascular Interventions
Issue number1
StatePublished - Jan 1 2014

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine


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