Radiation recall dermatitis with cefotetan: A case study

Ayodele Ayoola, Joo Lee Young

    Research output: Contribution to journalArticle

    15 Citations (Scopus)

    Abstract

    Radiation recall dermatitis (RRD) is an inflammatory skin reaction that occurs in a previously irradiated body part following drug administration. This phenomenon may occur from days to years following exposure to ionizing radiation. The case of a 54-year-old Caucasian woman who was initially treated with external-beam radiation to the right thoracic region following the diagnosis of a poorly differentiated squamous cell carcinoma of the right lung is reported. She received four cycles of consolidated chemotherapy with docetaxel and carboplatin. Four months later, she was admitted to the hospital for acute cholecystitis and was placed on cefotetan. She developed a tender, erythematous rash on the posterior region of her right thorax 48 hours later. The drug was withdrawn, supportive care was instituted, and the patient subsequently improved. RRD should be suspected in patients who develop an erythematous rash in a previously irradiated region. To our knowledge this entity has not been associated with cefotetan previously.

    Original languageEnglish (US)
    Pages (from-to)1118-1120
    Number of pages3
    JournalOncologist
    Volume11
    Issue number10
    DOIs
    StatePublished - Nov 1 2006

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    Radiodermatitis
    Cefotetan
    docetaxel
    Exanthema
    Thorax
    Acute Cholecystitis
    Carboplatin
    Ionizing Radiation
    Human Body
    Pharmaceutical Preparations
    Squamous Cell Carcinoma
    Radiation
    Drug Therapy
    Lung
    Skin

    All Science Journal Classification (ASJC) codes

    • Oncology
    • Cancer Research

    Cite this

    Ayoola, Ayodele ; Young, Joo Lee. / Radiation recall dermatitis with cefotetan : A case study. In: Oncologist. 2006 ; Vol. 11, No. 10. pp. 1118-1120.
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    abstract = "Radiation recall dermatitis (RRD) is an inflammatory skin reaction that occurs in a previously irradiated body part following drug administration. This phenomenon may occur from days to years following exposure to ionizing radiation. The case of a 54-year-old Caucasian woman who was initially treated with external-beam radiation to the right thoracic region following the diagnosis of a poorly differentiated squamous cell carcinoma of the right lung is reported. She received four cycles of consolidated chemotherapy with docetaxel and carboplatin. Four months later, she was admitted to the hospital for acute cholecystitis and was placed on cefotetan. She developed a tender, erythematous rash on the posterior region of her right thorax 48 hours later. The drug was withdrawn, supportive care was instituted, and the patient subsequently improved. RRD should be suspected in patients who develop an erythematous rash in a previously irradiated region. To our knowledge this entity has not been associated with cefotetan previously.",
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    Radiation recall dermatitis with cefotetan : A case study. / Ayoola, Ayodele; Young, Joo Lee.

    In: Oncologist, Vol. 11, No. 10, 01.11.2006, p. 1118-1120.

    Research output: Contribution to journalArticle

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    T2 - A case study

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    AU - Young, Joo Lee

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    AB - Radiation recall dermatitis (RRD) is an inflammatory skin reaction that occurs in a previously irradiated body part following drug administration. This phenomenon may occur from days to years following exposure to ionizing radiation. The case of a 54-year-old Caucasian woman who was initially treated with external-beam radiation to the right thoracic region following the diagnosis of a poorly differentiated squamous cell carcinoma of the right lung is reported. She received four cycles of consolidated chemotherapy with docetaxel and carboplatin. Four months later, she was admitted to the hospital for acute cholecystitis and was placed on cefotetan. She developed a tender, erythematous rash on the posterior region of her right thorax 48 hours later. The drug was withdrawn, supportive care was instituted, and the patient subsequently improved. RRD should be suspected in patients who develop an erythematous rash in a previously irradiated region. To our knowledge this entity has not been associated with cefotetan previously.

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