Radiation therapy in the management of patients with unresectable stage IIIA and IIIB non-small cell lung cancer

Research output: Contribution to journalReview article

12 Citations (Scopus)

Abstract

Treatment of patients with unresectable stage Ilia and IIIB non-small cell lung cancer with conventional radiation therapy has resulted in poor local control, a high rate of systemic failure, and 5-year survival of less than 10%. Recent modification in radiation treatment planning, dose delivery, and fractionization has demonstrated significantly improved median and 2- year survival, comparable in some trials to that achieved with induction chemotherapy followed by radiation. Current trials focus on combining systemic therapy with dose-intense radiation therapy to improve with local and systemic control.

Original languageEnglish (US)
Pages (from-to)423-428
Number of pages6
JournalSeminars in Oncology
Volume24
Issue number4
StatePublished - 1997

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Non-Small Cell Lung Carcinoma
Radiotherapy
Radiation
Ilium
Induction Chemotherapy
Survival
Therapeutics

All Science Journal Classification (ASJC) codes

  • Hematology
  • Oncology

Cite this

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title = "Radiation therapy in the management of patients with unresectable stage IIIA and IIIB non-small cell lung cancer",
abstract = "Treatment of patients with unresectable stage Ilia and IIIB non-small cell lung cancer with conventional radiation therapy has resulted in poor local control, a high rate of systemic failure, and 5-year survival of less than 10{\%}. Recent modification in radiation treatment planning, dose delivery, and fractionization has demonstrated significantly improved median and 2- year survival, comparable in some trials to that achieved with induction chemotherapy followed by radiation. Current trials focus on combining systemic therapy with dose-intense radiation therapy to improve with local and systemic control.",
author = "{Wagner Jr.}, Henry",
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journal = "Seminars in Oncology",
issn = "0093-7754",
publisher = "W.B. Saunders Ltd",
number = "4",

}

Radiation therapy in the management of patients with unresectable stage IIIA and IIIB non-small cell lung cancer. / Wagner Jr., Henry.

In: Seminars in Oncology, Vol. 24, No. 4, 1997, p. 423-428.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Radiation therapy in the management of patients with unresectable stage IIIA and IIIB non-small cell lung cancer

AU - Wagner Jr., Henry

PY - 1997

Y1 - 1997

N2 - Treatment of patients with unresectable stage Ilia and IIIB non-small cell lung cancer with conventional radiation therapy has resulted in poor local control, a high rate of systemic failure, and 5-year survival of less than 10%. Recent modification in radiation treatment planning, dose delivery, and fractionization has demonstrated significantly improved median and 2- year survival, comparable in some trials to that achieved with induction chemotherapy followed by radiation. Current trials focus on combining systemic therapy with dose-intense radiation therapy to improve with local and systemic control.

AB - Treatment of patients with unresectable stage Ilia and IIIB non-small cell lung cancer with conventional radiation therapy has resulted in poor local control, a high rate of systemic failure, and 5-year survival of less than 10%. Recent modification in radiation treatment planning, dose delivery, and fractionization has demonstrated significantly improved median and 2- year survival, comparable in some trials to that achieved with induction chemotherapy followed by radiation. Current trials focus on combining systemic therapy with dose-intense radiation therapy to improve with local and systemic control.

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M3 - Review article

VL - 24

SP - 423

EP - 428

JO - Seminars in Oncology

JF - Seminars in Oncology

SN - 0093-7754

IS - 4

ER -