Treatment of patients with unresectable stage Ilia and IIIB non-small cell lung cancer with conventional radiation therapy has resulted in poor local control, a high rate of systemic failure, and 5-year survival of less than 10%. Recent modification in radiation treatment planning, dose delivery, and fractionization has demonstrated significantly improved median and 2- year survival, comparable in some trials to that achieved with induction chemotherapy followed by radiation. Current trials focus on combining systemic therapy with dose-intense radiation therapy to improve with local and systemic control.
|Original language||English (US)|
|Number of pages||6|
|Journal||Seminars in Oncology|
|Publication status||Published - 1997|
All Science Journal Classification (ASJC) codes