Rapid determination of particle velocity from space-time images using the Radon transform

Patrick J. Drew, Pablo Blinder, Gert Cauwenberghs, Andy Y. Shih, David Kleinfeld

Research output: Contribution to journalArticlepeer-review

77 Scopus citations

Abstract

Laser-scanning methods are a means to observe streaming particles, such as the flow of red blood cells in a blood vessel. Typically, particle velocity is extracted from images formed from cyclically repeated line-scan data that is obtained along the center-line of the vessel; motion leads to streaks whose angle is a function of the velocity. Past methods made use of shearing or rotation of the images and a Singular Value Decomposition (SVD) to automatically estimate the average velocity in a temporal window of data. Here we present an alternative method that makes use of the Radon transform to calculate the velocity of streaming particles. We show that this method is over an order of magnitude faster than the SVD-based algorithm and is more robust to noise.

Original languageEnglish (US)
Pages (from-to)5-11
Number of pages7
JournalJournal of Computational Neuroscience
Volume29
Issue number1-2
DOIs
StatePublished - Aug 2010

All Science Journal Classification (ASJC) codes

  • Sensory Systems
  • Cognitive Neuroscience
  • Cellular and Molecular Neuroscience

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