Rapid Turn-On Fluorescence Detection of Copper(II): Aromatic Substituent Effects on the Response Rate

Jiyoung Jung, Junyong Jo, Adriana Dinescu

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Oxidative cyclization of o-phenylazo aniline was utilized as a turn-on fluorescent probe of the copper(II) ion. The number and the position of electron donating groups on the probes were systematically varied to investigate the effect of aryl substituent on reactivity toward copper ion. Among the series of analogous probes, the 2,4,6-trimethoxy substituted probe exhibits not only a faster (40-times faster) reaction but also a lower detection limit (20 times lower) than previously reported probes under identical conditions. The comparative kinetic studies reveal that both the number and the position of substitution have a significant impact on the reactivity toward copper, which will be discussed in the manuscript.

Original languageEnglish (US)
Pages (from-to)1689-1693
Number of pages5
JournalOrganic Process Research and Development
Volume21
Issue number10
DOIs
StatePublished - Oct 20 2017

All Science Journal Classification (ASJC) codes

  • Physical and Theoretical Chemistry
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Rapid Turn-On Fluorescence Detection of Copper(II): Aromatic Substituent Effects on the Response Rate'. Together they form a unique fingerprint.

Cite this