TY - JOUR
T1 - Reaction pathways and kinetics of cholesterol in high-temperature water
AU - Hietala, David C.
AU - Savage, Phillip E.
N1 - Funding Information:
We thank Thomas Yeh for discussions about gas chromatography analysis. We acknowledge Jennifer Jocz for discussions of experimental methods employed. We are grateful for the financial support from the National Science Foundation ( EFRI-1332342 ) and the University of Michigan .
Publisher Copyright:
© 2014 Elsevier B.V.
PY - 2015
Y1 - 2015
N2 - We investigated the reaction of cholesterol, a model compound for sterols in microalgae, in high-temperature water at 300, 325, and 350°C. Products nearly entirely consisted of cholestadienes, with cholesta-2,4-diene, cholesta-3,5-diene, and cholesta-4,6-diene being the most abundant isomers. Cholesta-3,5-diene was the only primary product, formed via dehydration of cholesterol. Cholesta-2,4-diene and cholesta-4,6-diene likely formed from cholesta-3,5-diene by double-bond migration. We report conversion and product molar yields for each reaction condition. The initial rate of disappearance of cholesterol was first-order with an activation energy of Ea=127±12kJmol-1 and A=108.35±2.41s-1. We used a delplot analysis and mechanistic considerations to develop a reaction network for conditions relevant to hydrothermal liquefaction of microalgae.
AB - We investigated the reaction of cholesterol, a model compound for sterols in microalgae, in high-temperature water at 300, 325, and 350°C. Products nearly entirely consisted of cholestadienes, with cholesta-2,4-diene, cholesta-3,5-diene, and cholesta-4,6-diene being the most abundant isomers. Cholesta-3,5-diene was the only primary product, formed via dehydration of cholesterol. Cholesta-2,4-diene and cholesta-4,6-diene likely formed from cholesta-3,5-diene by double-bond migration. We report conversion and product molar yields for each reaction condition. The initial rate of disappearance of cholesterol was first-order with an activation energy of Ea=127±12kJmol-1 and A=108.35±2.41s-1. We used a delplot analysis and mechanistic considerations to develop a reaction network for conditions relevant to hydrothermal liquefaction of microalgae.
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U2 - 10.1016/j.cej.2014.12.020
DO - 10.1016/j.cej.2014.12.020
M3 - Article
AN - SCOPUS:84937211126
SN - 1385-8947
VL - 265
SP - 129
EP - 137
JO - Chemical Engineering Journal
JF - Chemical Engineering Journal
IS - 1
ER -