Reduced energy intake and weight loss on a legume-enriched diet lead to improvements in biomarkers related to chronic disease

Terryl J. Hartman, Zhiying Zhang, Paul S. Albert, Deborah Bagshaw, Roycelynn Mentor-Marcel, Diane C. Mitchell, Nancy H. Colburn, Penny M. Kris-Etherton, Elaine Lanza

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

The Legume Inflammation Feeding Experiment was a randomized crossover feeding trial of a legume-enriched (250 g/d) diet among men (n = 64) characterized for colorectal adenoma and insulin resistance status. A subset of participants (n = 44) completed a third, optional 4-week period, which encouraged weight loss. Participants significantly decreased energy intake (-770.3 kcal/d) and energy density (-0.45). We observed a 4.4% decrease in weight (-4.0 + 0.4 kg), accompanied by reductions in fasting plasma glucose (-5.7%), insulin (-15.8%), serum C-peptide (-17.4%), C-reactive protein (-32.7%), soluble tumor necrosis factor α receptor I (-42%), total (-13.3%), and low-density lipoprotein cholesterol (-15.6 %). A legume-enriched low energy density diet may promote weight loss.

Original languageEnglish (US)
Pages (from-to)208-215
Number of pages8
JournalTopics in Clinical Nutrition
Volume26
Issue number3
DOIs
StatePublished - Jul 1 2011

All Science Journal Classification (ASJC) codes

  • Nutrition and Dietetics

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