Refining the phenotype of borderline personality disorder

Diagnostic criteria and beyond

Michael Nelson Hallquist, Paul A. Pilkonis

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

Borderline personality disorder (BPD) is a heterogeneous disorder, and previous analyses have parsed its phenotype in terms of subtypes or underlying traits. We refined the BPD construct by testing a range of latent variable models to ascertain whether BPD is composed of traits, latent classes, or both. We also tested whether subtypes of BPD could be distinguished by anger, aggressiveness, antisocial behavior, and mistrustfulness, additional putative indicators drawn from Kernberg's (1967, 1975) theory of BPD. In a mixed clinical and nonclinical sample (N = 362), a factor mixture model consisting of two latent classes (symptomatic and asymptomatic) and a single severity dimension fit the BPD criteria, as defined by the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV), data better than latent class or factor analytic approaches. In the second analytic phase, finite mixture modeling of the symptomatic latent class (n = 100) revealed four BPD subtypes: angry/aggressive, angry/mistrustful, poor identity/low anger, and prototypical. Our results support a hybrid categorical-dimensional model of the BPD DSM-IV criteria. The BPD subtypes emerging from this model have important implications for treatment and etiological research.

Original languageEnglish (US)
Pages (from-to)228-246
Number of pages19
JournalPersonality Disorders: Theory, Research, and Treatment
Volume3
Issue number3
DOIs
StatePublished - Jul 1 2012

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Borderline Personality Disorder
Phenotype
Diagnostic and Statistical Manual of Mental Disorders
Anger

All Science Journal Classification (ASJC) codes

  • Clinical Psychology
  • Psychiatry and Mental health

Cite this

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Refining the phenotype of borderline personality disorder : Diagnostic criteria and beyond. / Hallquist, Michael Nelson; Pilkonis, Paul A.

In: Personality Disorders: Theory, Research, and Treatment, Vol. 3, No. 3, 01.07.2012, p. 228-246.

Research output: Contribution to journalArticle

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