Regulation of antiviral CD8+ T cells by inhibitory natural killer cell receptors

Anthony M. Byers, Christopher C. Kemball, Nicolas P. Andrews, Aron E. Lukacher

Research output: Contribution to journalReview articlepeer-review

9 Scopus citations

Abstract

Recent evidence indicates that CD8+ T cells express natural killer cell receptors that constrain the range and magnitude of their activities. For virus-specific CD8+ T cells, upregulation of these receptors serves to control infection, while concurrently minimizing bystander pathology. Dysregulated expression of these receptors, however, may foster the establishment of persistent virus infection.

Original languageEnglish (US)
Pages (from-to)169-177
Number of pages9
JournalMicrobes and Infection
Volume5
Issue number2
DOIs
StatePublished - Feb 1 2003

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Immunology
  • Infectious Diseases

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