Regulation of cell cycle synchronization by decapentaplegic during Drosophila eye development

Andrea Penton, Scott Brian Selleck, F. Michael Hoffmann

Research output: Contribution to journalArticle

73 Scopus citations

Abstract

In the developing Drosophila eye, differentiation is coordinated with synchronized progression through the cell cycle. Signaling mediated by the transforming growth factor-β-related gene decapentaplegic (dpp) was required for the synchronization of the cell cycle but not for cell fate specification. DPP may affect cell cycle synchronization by promoting cell cycle progression through the G2-M phases. This synchronization is critical for the precise assembly of the eye.

Original languageEnglish (US)
Pages (from-to)203-206
Number of pages4
JournalScience
Volume275
Issue number5297
DOIs
StatePublished - Jan 10 1997

All Science Journal Classification (ASJC) codes

  • General

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