Relationship between Blood Serum Insulin-Like Growth Factor I Concentration and Postweaning Feed Efficiency of Crossbred Cattle at Three Levels of Dietary Intake

D. A. Stick, M. E. Davis, S. C. Loerch, R. C.M. Simmer

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

Blood serum concentration of IGF-I was analyzed to determine its relationship with individual postweaning feed efficiency (gain/feed) of 36 crossbred steer calves fed at three levels of feed intake (n = 12 at each level). Diets consisted of a corn silage-based growing diet for 84 d followed by a 91% concentrate finishing diet for 56 d. Dietary intake levels were at 80, 90, or 100% of ad libitum. Diets were formulated to ensure equal daily intake of protein, vitamins, and minerals across intake treatment levels. Intake was measured daily; ADG, DMI, and feed efficiency were calculated at 28-d intervals, through d 140. Individual weights and serum samples were collected at the beginning of the study and at 28-d intervals thereafter. The IGF-I concentrations were determined with a RIA. Data were analyzed as a multivariate split-plot in time. Imposed dietary intake restrictions did not affect serum IGF-I concentration (P = .90) or individual feed efficiency (P = .36), even though the least squares means for IGF-I concentration tended to decrease and the feed efficiency means tended to increase under the restricted intake levels. Serum IGF-I concentration, ADG, and feed efficiency were affected (P < .001) by collection date. Residual correlations between IGF-I concentrations at adjacent 28-d sampling times averaged .72. Diet intake level × sampling time interactions existed for ADG (P = .02) and feed efficiency (P < .001). Positive residual correlations of .28 (P < .001) and .16 (P = .07) existed between IGF-I and ADG and between IGF-I and feed efficiency, respectively. Regression analysis indicated that a 1 ng/mL increase in serum IGF-I concentration was associated with a .00135 kg/d increase in ADG (P < .001) and a .0001 kg gain/kg feed increase in feed efficiency (P = .04). These results support the hypothesis that serum IGF-I plays a role in growth and in efficiency of feed utilization in beef cattle.

Original languageEnglish (US)
Pages (from-to)498-505
Number of pages8
JournalJournal of animal science
Volume76
Issue number2
DOIs
StatePublished - Feb 1998

Fingerprint

insulin-like growth factor I
blood serum
Insulin-Like Growth Factor I
food intake
crossbreds
feed conversion
cattle
Serum
Diet
diet
Silage
Least-Squares Analysis
protein intake
corn silage
Vitamins
sampling
beef cattle
Zea mays
Minerals
least squares

All Science Journal Classification (ASJC) codes

  • Food Science
  • Animal Science and Zoology
  • Genetics

Cite this

@article{783b3c86c85841b89510d9bb514d3599,
title = "Relationship between Blood Serum Insulin-Like Growth Factor I Concentration and Postweaning Feed Efficiency of Crossbred Cattle at Three Levels of Dietary Intake",
abstract = "Blood serum concentration of IGF-I was analyzed to determine its relationship with individual postweaning feed efficiency (gain/feed) of 36 crossbred steer calves fed at three levels of feed intake (n = 12 at each level). Diets consisted of a corn silage-based growing diet for 84 d followed by a 91{\%} concentrate finishing diet for 56 d. Dietary intake levels were at 80, 90, or 100{\%} of ad libitum. Diets were formulated to ensure equal daily intake of protein, vitamins, and minerals across intake treatment levels. Intake was measured daily; ADG, DMI, and feed efficiency were calculated at 28-d intervals, through d 140. Individual weights and serum samples were collected at the beginning of the study and at 28-d intervals thereafter. The IGF-I concentrations were determined with a RIA. Data were analyzed as a multivariate split-plot in time. Imposed dietary intake restrictions did not affect serum IGF-I concentration (P = .90) or individual feed efficiency (P = .36), even though the least squares means for IGF-I concentration tended to decrease and the feed efficiency means tended to increase under the restricted intake levels. Serum IGF-I concentration, ADG, and feed efficiency were affected (P < .001) by collection date. Residual correlations between IGF-I concentrations at adjacent 28-d sampling times averaged .72. Diet intake level × sampling time interactions existed for ADG (P = .02) and feed efficiency (P < .001). Positive residual correlations of .28 (P < .001) and .16 (P = .07) existed between IGF-I and ADG and between IGF-I and feed efficiency, respectively. Regression analysis indicated that a 1 ng/mL increase in serum IGF-I concentration was associated with a .00135 kg/d increase in ADG (P < .001) and a .0001 kg gain/kg feed increase in feed efficiency (P = .04). These results support the hypothesis that serum IGF-I plays a role in growth and in efficiency of feed utilization in beef cattle.",
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Relationship between Blood Serum Insulin-Like Growth Factor I Concentration and Postweaning Feed Efficiency of Crossbred Cattle at Three Levels of Dietary Intake. / Stick, D. A.; Davis, M. E.; Loerch, S. C.; Simmer, R. C.M.

In: Journal of animal science, Vol. 76, No. 2, 02.1998, p. 498-505.

Research output: Contribution to journalArticle

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