Abstract
Basal release of Gn-RH from perifused medial-basal hypothalami of rats was at or below levels detectable by radioimmunoassay. Infusion of norepinephrine, dopamine, acetylcholine or serotonin (0.1–10 mM) as 10–20 min pulses was not associated with a detectable increase of Gn-RH in the effluent. However, 10–20 min pulses of melatonin (0.1–1.0 mM) consistently caused release of Gn-RH.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1723-1726 |
| Number of pages | 4 |
| Journal | Endocrinology |
| Volume | 100 |
| Issue number | 6 |
| DOIs | |
| State | Published - Jun 1977 |
All Science Journal Classification (ASJC) codes
- Endocrinology
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Kao, L. W. L., & Weisz, J. (1977). Release of gonadotrophin-releasing hormone (Gn-Rh) from isolated, perifused medial-basal hypothalamus by melatonin. Endocrinology, 100(6), 1723-1726. https://doi.org/10.1210/endo-100-6-1723