Abstract
Basal release of Gn-RH from perifused medial-basal hypothalami of rats was at or below levels detectable by radioimmunoassay. Infusion of norepinephrine, dopamine, acetylcholine or serotonin (0.1–10 mM) as 10–20 min pulses was not associated with a detectable increase of Gn-RH in the effluent. However, 10–20 min pulses of melatonin (0.1–1.0 mM) consistently caused release of Gn-RH.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1723-1726 |
| Number of pages | 4 |
| Journal | Endocrinology |
| Volume | 100 |
| Issue number | 6 |
| DOIs | |
| State | Published - Jun 1977 |
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All Science Journal Classification (ASJC) codes
- Endocrinology
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Release of gonadotrophin-releasing hormone (Gn-Rh) from isolated, perifused medial-basal hypothalamus by melatonin. / Kao, Lidia Wei Liu; Weisz, Judith.
In: Endocrinology, Vol. 100, No. 6, 06.1977, p. 1723-1726.Research output: Contribution to journal › Article
TY - JOUR
T1 - Release of gonadotrophin-releasing hormone (Gn-Rh) from isolated, perifused medial-basal hypothalamus by melatonin
AU - Kao, Lidia Wei Liu
AU - Weisz, Judith
PY - 1977/6
Y1 - 1977/6
N2 - Basal release of Gn-RH from perifused medial-basal hypothalami of rats was at or below levels detectable by radioimmunoassay. Infusion of norepinephrine, dopamine, acetylcholine or serotonin (0.1–10 mM) as 10–20 min pulses was not associated with a detectable increase of Gn-RH in the effluent. However, 10–20 min pulses of melatonin (0.1–1.0 mM) consistently caused release of Gn-RH.
AB - Basal release of Gn-RH from perifused medial-basal hypothalami of rats was at or below levels detectable by radioimmunoassay. Infusion of norepinephrine, dopamine, acetylcholine or serotonin (0.1–10 mM) as 10–20 min pulses was not associated with a detectable increase of Gn-RH in the effluent. However, 10–20 min pulses of melatonin (0.1–1.0 mM) consistently caused release of Gn-RH.
UR - http://www.scopus.com/inward/record.url?scp=0017682235&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0017682235&partnerID=8YFLogxK
U2 - 10.1210/endo-100-6-1723
DO - 10.1210/endo-100-6-1723
M3 - Article
C2 - 322999
AN - SCOPUS:0017682235
VL - 100
SP - 1723
EP - 1726
JO - Endocrinology
JF - Endocrinology
SN - 0013-7227
IS - 6
ER -