Release of gonadotrophin-releasing hormone (Gn-Rh) from isolated, perifused medial-basal hypothalamus by melatonin

Lidia Wei Liu Kao; Judith Weisz

doi:10.1210/endo-100-6-1723

Release of gonadotrophin-releasing hormone (Gn-Rh) from isolated, perifused medial-basal hypothalamus by melatonin

Lidia Wei Liu Kao, Judith Weisz

Department of Obstetrics and Gynecology

Research output: Contribution to journal › Article › peer-review

48 Scopus citations

Abstract

Basal release of Gn-RH from perifused medial-basal hypothalami of rats was at or below levels detectable by radioimmunoassay. Infusion of norepinephrine, dopamine, acetylcholine or serotonin (0.1–10 mM) as 10–20 min pulses was not associated with a detectable increase of Gn-RH in the effluent. However, 10–20 min pulses of melatonin (0.1–1.0 mM) consistently caused release of Gn-RH.

Original language	English (US)
Pages (from-to)	1723-1726
Number of pages	4
Journal	Endocrinology
Volume	100
Issue number	6
DOIs	https://doi.org/10.1210/endo-100-6-1723
State	Published - Jun 1977

All Science Journal Classification (ASJC) codes

Endocrinology

Access to Document

10.1210/endo-100-6-1723

Fingerprint Dive into the research topics of 'Release of gonadotrophin-releasing hormone (Gn-Rh) from isolated, perifused medial-basal hypothalamus by melatonin'. Together they form a unique fingerprint.

Cite this

@article{53e605b015f24939823017f63d26f5b2,

title = "Release of gonadotrophin-releasing hormone (Gn-Rh) from isolated, perifused medial-basal hypothalamus by melatonin",

abstract = "Basal release of Gn-RH from perifused medial-basal hypothalami of rats was at or below levels detectable by radioimmunoassay. Infusion of norepinephrine, dopamine, acetylcholine or serotonin (0.1–10 mM) as 10–20 min pulses was not associated with a detectable increase of Gn-RH in the effluent. However, 10–20 min pulses of melatonin (0.1–1.0 mM) consistently caused release of Gn-RH.",

author = "Kao, {Lidia Wei Liu} and Judith Weisz",

year = "1977",

month = jun,

doi = "10.1210/endo-100-6-1723",

language = "English (US)",

volume = "100",

pages = "1723--1726",

journal = "Endocrinology",

issn = "0013-7227",

publisher = "The Endocrine Society",

number = "6",

}

TY - JOUR

T1 - Release of gonadotrophin-releasing hormone (Gn-Rh) from isolated, perifused medial-basal hypothalamus by melatonin

AU - Kao, Lidia Wei Liu

AU - Weisz, Judith

PY - 1977/6

Y1 - 1977/6

N2 - Basal release of Gn-RH from perifused medial-basal hypothalami of rats was at or below levels detectable by radioimmunoassay. Infusion of norepinephrine, dopamine, acetylcholine or serotonin (0.1–10 mM) as 10–20 min pulses was not associated with a detectable increase of Gn-RH in the effluent. However, 10–20 min pulses of melatonin (0.1–1.0 mM) consistently caused release of Gn-RH.

AB - Basal release of Gn-RH from perifused medial-basal hypothalami of rats was at or below levels detectable by radioimmunoassay. Infusion of norepinephrine, dopamine, acetylcholine or serotonin (0.1–10 mM) as 10–20 min pulses was not associated with a detectable increase of Gn-RH in the effluent. However, 10–20 min pulses of melatonin (0.1–1.0 mM) consistently caused release of Gn-RH.

UR - http://www.scopus.com/inward/record.url?scp=0017682235&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0017682235&partnerID=8YFLogxK

U2 - 10.1210/endo-100-6-1723

DO - 10.1210/endo-100-6-1723

M3 - Article

C2 - 322999

AN - SCOPUS:0017682235

VL - 100

SP - 1723

EP - 1726

JO - Endocrinology

JF - Endocrinology

SN - 0013-7227

IS - 6

ER -

Release of gonadotrophin-releasing hormone (Gn-Rh) from isolated, perifused medial-basal hypothalamus by melatonin

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Cite this