Renin producing Wilms' tumor

John Spahr, Laurence M. Demers, Stephen J. Shochat

Research output: Contribution to journalArticlepeer-review

29 Scopus citations

Abstract

A 4-yr-old boy with Wilms' tumor, hypertension, and hyperreninemia is presented. Three times as much renin was extracted from tumor tissue as from adjacent renal parenchyma, suggesting that the tumor itself was the primary source of the renin and cause of the hypertension. Other reported cases of hypertension and increased renin production with Wilms' tumor are reviewed. Hypertension is a very frequent finding in patients presenting with Wilms' tumor. The possibility that many of these neoplasms may be found to hypersecrete renin if properly investigated is discussed.

Original languageEnglish (US)
Pages (from-to)32-34
Number of pages3
JournalJournal of pediatric surgery
Volume16
Issue number1
DOIs
StatePublished - Feb 1981

All Science Journal Classification (ASJC) codes

  • Surgery
  • Pediatrics, Perinatology, and Child Health

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