Resistance to quorum-quenching compounds

Rodolfo García-Contreras, Toshinari Maeda, Thomas K. Wood

Research output: Contribution to journalReview article

57 Citations (Scopus)

Abstract

Bacteria have the remarkable ability to communicate as a group in what has become known as quorum sensing (QS), and this trait has been associated with important bacterial phenotypes, such as virulence and biofilm formation. Bacteria also have an incredible ability to evolve resistance to all known antimicrobials. Hence, although inhibition of QS has been hailed as a means to reduce virulence in a manner that is impervious to bacterial resistance mechanisms, this approach is unlikely to be a panacea. Here we review the evidence that bacteria can evolve resistance to quorum-quenching compounds.

Original languageEnglish (US)
Pages (from-to)6840-6846
Number of pages7
JournalApplied and environmental microbiology
Volume79
Issue number22
DOIs
StatePublished - Nov 1 2013

Fingerprint

Quorum Sensing
quorum sensing
virulence
Bacteria
bacterium
Virulence
bacteria
Biofilms
resistance mechanisms
biofilm
phenotype
anti-infective agents
Phenotype

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Food Science
  • Applied Microbiology and Biotechnology
  • Ecology

Cite this

García-Contreras, Rodolfo ; Maeda, Toshinari ; Wood, Thomas K. / Resistance to quorum-quenching compounds. In: Applied and environmental microbiology. 2013 ; Vol. 79, No. 22. pp. 6840-6846.
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Resistance to quorum-quenching compounds. / García-Contreras, Rodolfo; Maeda, Toshinari; Wood, Thomas K.

In: Applied and environmental microbiology, Vol. 79, No. 22, 01.11.2013, p. 6840-6846.

Research output: Contribution to journalReview article

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