Resistant starch: impact on the gut microbiome and health

Peter DeMartino, Darrell W. Cockburn

Research output: Contribution to journalReview article

Abstract

Resistant starch has received a lot of attention for its potential to exert a healthy impact on the gut and certain members of its resident microbiota, particularly through enhanced butyrate production. However, resistant starch is a broad category that encompasses several structurally different starches. While all resist digestion by human enzymes, they differ in their effects on the microbiota. Individual variation in microbiota composition also has a substantial influence on butyrate production. Research on this interaction between resistant starch and the microbiota is using in vitro fermentations, cross-over design clinical trials and mouse studies with isotopically labeled starch. These studies are demonstrating that more personalized approaches are needed for finding resistant starch or other fiber that will promote a healthy gut.

Original languageEnglish (US)
Pages (from-to)66-71
Number of pages6
JournalCurrent Opinion in Biotechnology
Volume61
DOIs
StatePublished - Feb 2020

Fingerprint

Starch
Microbiota
Health
Butyrates
Cross-Over Studies
Fermentation
Gastrointestinal Microbiome
Digestion
Enzymes
Clinical Trials
Fibers
Chemical analysis
Research

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Bioengineering
  • Biomedical Engineering

Cite this

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Resistant starch : impact on the gut microbiome and health. / DeMartino, Peter; Cockburn, Darrell W.

In: Current Opinion in Biotechnology, Vol. 61, 02.2020, p. 66-71.

Research output: Contribution to journalReview article

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