Restriction endonuclease cleavage map of the DNA of JC virus

J. D. Martin, R. J. Frisque, B. L. Padgett, D. L. Walker

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

A physical map of the sites cleaved by the following restriction endonucleases was derived for the DNA of JC virus, a human polyomavirus: EcoRI, HpaI, and PstI (one site each); HindII (four sites); and HindIII (three sites). By agarose gel electrophoresis of fragmented DNA, the size of full-length DNA of JC virus was estimated to be 5,125 ± 105 base pairs (98 ± 2% of the length of simian virus 40 DNA).

Original languageEnglish (US)
Pages (from-to)846-855
Number of pages10
JournalJournal of virology
Volume29
Issue number3
DOIs
StatePublished - 1979

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Immunology
  • Insect Science
  • Virology

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