Retention of ionic and non-ionic catechols in capillary zone electrophoresis with micellar solutions

Ross A. Wallingford, Andrew G. Ewing

Research output: Contribution to journalArticlepeer-review

Abstract

The use of micellar solutions in capillary zone electrophoresis has been primarily relegated to separations of non-ionic solutes, while its applicability to cationic species has been unexplored. We have found that the use of sodium dodecyl sulfate micelles in phosphate buffer allows for tremendous gains in selectivity for several cationic and non-ionic catechols over what can be obtained with normal capillary zone electrophoresis. Complexation of catechols with boric acid alters the net charge on the solutes and changes the partitioning behavior to produce adequate selectivity with improved analysis times. Although the mechanisms of solute interaction with the micellar phase for the cationic species are not decisively known, evidence is presented supporting the existence of ion-pairing equilibria simultaneously accompanied by micellar solubilization.

Original languageEnglish (US)
Pages (from-to)299-309
Number of pages11
JournalJournal of Chromatography A
Volume441
Issue number2
DOIs
StatePublished - 1988

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Biochemistry
  • Organic Chemistry

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