Retrograde flow through bileaflet mechanical heart valves

Ajit P. Yoganathan, Arnold Anthony Fontaine, Jeffrey T. Ellis, Timothy M. Healy

Research output: Contribution to journalArticle

Abstract

In vitro experiments were conducted to investigate the time-varying retrograde flow characteristics of 27 mm bileaflet aortic valves. The retrograde flow fields of bileaflet valves range from uniform squeeze flow and regurgitant jet flow fields to flow fields involving complex secondary flows. Stress levels are sufficiently high to cause cell damage or activation in both the squeeze and jet flows. The squeeze occur over a shorter time span but encompass a larger area of flow and potential exposure to more cells. It is speculated that valves exhibiting complex flow patterns have lower incidence of thrombus due to increased washing of the hinge region and valve perimeter by these flow patterns. These results, and the test protocol developed in this study, may improve future capabilities for predicting thrombus potential in new valve designs.

Original languageEnglish (US)
Pages (from-to)211-212
Number of pages2
JournalMedical and Biological Engineering and Computing
Volume34
Issue numberSUPPL. 1
StatePublished - 1996

Fingerprint

Heart Valves
Flow fields
Thrombosis
Flow patterns
Aortic Valve
Secondary flow
Hinges
Washing
Incidence
Chemical activation
Cells
Experiments
In Vitro Techniques

All Science Journal Classification (ASJC) codes

  • Computational Theory and Mathematics
  • Computer Science Applications
  • Biomedical Engineering
  • Health Informatics
  • Health Information Management

Cite this

Yoganathan, A. P., Fontaine, A. A., Ellis, J. T., & Healy, T. M. (1996). Retrograde flow through bileaflet mechanical heart valves. Medical and Biological Engineering and Computing, 34(SUPPL. 1), 211-212.
Yoganathan, Ajit P. ; Fontaine, Arnold Anthony ; Ellis, Jeffrey T. ; Healy, Timothy M. / Retrograde flow through bileaflet mechanical heart valves. In: Medical and Biological Engineering and Computing. 1996 ; Vol. 34, No. SUPPL. 1. pp. 211-212.
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Yoganathan, AP, Fontaine, AA, Ellis, JT & Healy, TM 1996, 'Retrograde flow through bileaflet mechanical heart valves', Medical and Biological Engineering and Computing, vol. 34, no. SUPPL. 1, pp. 211-212.

Retrograde flow through bileaflet mechanical heart valves. / Yoganathan, Ajit P.; Fontaine, Arnold Anthony; Ellis, Jeffrey T.; Healy, Timothy M.

In: Medical and Biological Engineering and Computing, Vol. 34, No. SUPPL. 1, 1996, p. 211-212.

Research output: Contribution to journalArticle

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