What are big questions? Why do scholars propose them? How are they generated? Could they be valuable and useful in HCI research? In this paper we conduct a thorough review of "big questions" literature, which draws on scholarship from a variety of fields and disciplines. Our intended contribution is twofold. First, we provide a substantive review of big questions scholarship, which to our knowledge has never been done before. Second, we leverage this summary as a means of examining the value and utility of big questions in HCI as a research discipline. Whether HCI decides that generating and having big questions would be a desirable path forward, we believe that examining the potential for big questions is a useful way of becoming more reflective about HCI research. Copyright is held by the owner/author(s).