Ring-closing metathesis of vinyl chlorides for formation of 5-, 6- and 7-membered carbocyclic and heterocyclic systems

Wenchun Chao, Matthew L. Meketa, Steven M. Weinreb

Research output: Contribution to journalReview articlepeer-review

32 Scopus citations

Abstract

Ring-closing metathesis (RCM) of olefinic vinyl chlorides can be effected using the second generation Grubb's catalyst 18 (10 mol%, deoxygenated benzene, 65°C) to assemble a variety of carbocyclic and heterocyclic 5, 6 and 7-membered rings in high yields.

Original languageEnglish (US)
Pages (from-to)2058-2061
Number of pages4
JournalSynthesis
Issue number12
DOIs
StatePublished - Aug 19 2004

All Science Journal Classification (ASJC) codes

  • Organic Chemistry

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