Ring-closing metathesis of vinyl chlorides for formation of 5-, 6- and 7-membered carbocyclic and heterocyclic systems

Wenchun Chao; Matthew L. Meketa; Steven M. Weinreb

doi:10.1055/s-2004-822327

Ring-closing metathesis of vinyl chlorides for formation of 5-, 6- and 7-membered carbocyclic and heterocyclic systems

Wenchun Chao, Matthew L. Meketa, Steven M. Weinreb

Chemistry

Research output: Contribution to journal › Review article › peer-review

32 Scopus citations

Abstract

Ring-closing metathesis (RCM) of olefinic vinyl chlorides can be effected using the second generation Grubb's catalyst 18 (10 mol%, deoxygenated benzene, 65°C) to assemble a variety of carbocyclic and heterocyclic 5, 6 and 7-membered rings in high yields.

Original language	English (US)
Pages (from-to)	2058-2061
Number of pages	4
Journal	Synthesis
Issue number	12
DOIs	https://doi.org/10.1055/s-2004-822327
State	Published - Aug 19 2004

All Science Journal Classification (ASJC) codes

Organic Chemistry

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10.1055/s-2004-822327

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title = "Ring-closing metathesis of vinyl chlorides for formation of 5-, 6- and 7-membered carbocyclic and heterocyclic systems",

abstract = "Ring-closing metathesis (RCM) of olefinic vinyl chlorides can be effected using the second generation Grubb's catalyst 18 (10 mol%, deoxygenated benzene, 65°C) to assemble a variety of carbocyclic and heterocyclic 5, 6 and 7-membered rings in high yields.",

author = "Wenchun Chao and Meketa, {Matthew L.} and Weinreb, {Steven M.}",

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AU - Chao, Wenchun

AU - Meketa, Matthew L.

AU - Weinreb, Steven M.

PY - 2004/8/19

Y1 - 2004/8/19

N2 - Ring-closing metathesis (RCM) of olefinic vinyl chlorides can be effected using the second generation Grubb's catalyst 18 (10 mol%, deoxygenated benzene, 65°C) to assemble a variety of carbocyclic and heterocyclic 5, 6 and 7-membered rings in high yields.

AB - Ring-closing metathesis (RCM) of olefinic vinyl chlorides can be effected using the second generation Grubb's catalyst 18 (10 mol%, deoxygenated benzene, 65°C) to assemble a variety of carbocyclic and heterocyclic 5, 6 and 7-membered rings in high yields.

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M3 - Review article

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JO - Synthesis (Germany)

JF - Synthesis (Germany)

SN - 0039-7881

IS - 12

ER -

Ring-closing metathesis of vinyl chlorides for formation of 5-, 6- and 7-membered carbocyclic and heterocyclic systems

Abstract

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