TY - JOUR
T1 - Risk Factors for Self-injurious Behavior in an Inpatient Psychiatric Sample of Children with Autism Spectrum Disorder
T2 - A Naturalistic Observation Study
AU - The Autism And Developmental Disorders Inpatient Research Collaborative (Addirc)
AU - Handen, Benjamin L.
AU - Mazefsky, Carla A.
AU - Gabriels, Robin L.
AU - Pedersen, Kahsi A.
AU - Wallace, Meredith
AU - Siegel, Matthew
AU - Erickson, Craig
AU - Gabriels, Robin L.
AU - Kaplan, Desmond
AU - Morrow, Eric M.
AU - Righi, Giulia
AU - Santangelo, Susan L.
AU - Wink, Logan
AU - Benevides, Jill
AU - Beresford, Carol
AU - Best, Carrie
AU - Bowen, Katie
AU - Dechant, Briar
AU - Dixon, Joanne
AU - Flis, Tom
AU - Gastgeb, Holly
AU - Geer, Angela
AU - Hagopian, Louis
AU - Handen, Benjamin
AU - Klever, Adam
AU - Lubetsky, Martin
AU - MacKenzie, Kristen
AU - Meservy, Zenoa
AU - McGonigle, John
AU - McGuire, Kelly
AU - McNeill, Faith
AU - Pedapati, Ernest
AU - Peura, Christine
AU - Pierri, Joseph
AU - Rogers, Christie
AU - Rossman, Brad
AU - Ruberg, Jennifer
AU - Small, Cathleen
AU - Stuckey, Nicole
AU - Tylenda, Barbara
AU - Verdi, Mary
AU - Vezzoli, Jessica
AU - Williams, Deanna
AU - Williams, Diane
AU - St. Germain, Donald L.
AU - Robinson, Girard
AU - Kasari, Connie
AU - King, Bryan
AU - McCracken, James
AU - McDougle, Christopher
N1 - Funding Information:
Funding This study was funded by the Simons Foundation Autism Research Initiative (SFARI #296318 to M.S.) and the Nancy Lurie Marks Family Foundation.
Funding Information:
The ADDIRC is made up of the co-investigators: Matthew Siegel, MD (PI) (Maine Medical Center Research Institute; Tufts University), Craig Erickson, MD (Cincinnati Children?s Hospital; University of Cincinnati), Robin L. Gabriels, PsyD (Children?s Hospital Colorado; University of Colorado), Desmond Kaplan, MD (Sheppard Pratt Health System), Carla A. Mazefsky, PhD (Western Psychiatric Institute and Clinic; University of Pittsburgh), Eric M. Morrow, MD, PhD (Bradley Hospital; Brown University), Giulia Righi, PhD (Bradley Hospital; Brown University), Susan L. Santangelo, ScD (Maine Medical Center Research Institute; Tufts University), and Logan Wink, MD (Cincinnati Children?s Hospital; University of Cincinnati). Collaborating investigators and staff: Jill Benevides, BS, Carol Beresford, MD, Carrie Best, MPH, Katie Bowen, LCSW, Briar Dechant, BS, Joanne Dixon, PhD, Tom Flis, BCBA, LCPC, Holly Gastgeb, PhD, Angela Geer, BS, Louis Hagopian, PhD, Benjamin Handen, PhD, BCBA-D, Adam Klever, BS, Martin Lubetsky, MD, Kristen MacKenzie, BS, Zenoa Meservy, MD, John McGonigle, PhD, Kelly McGuire, MD, Faith McNeill, BA, Ernest Pedapati, MD, Christine Peura, BA, Joseph Pierri, MD, Christie Rogers, MS, CCC-SLP, Brad Rossman, MA, Jennifer Ruberg, LISW, Cathleen Small, PhD, Kahsi A. Pedersen, PhD, Nicole Stuckey, MSN, RN, Barbara Tylenda, PhD, Mary Verdi, MA, Jessica Vezzoli, BS, Deanna Williams, BA, and Diane Williams, PhD, CCC-SLP. We gratefully acknowledge the contributions of the coordinating site advisory group: Donald L. St. Germain, MD and Girard Robinson, MD, and our scientific advisory group: Connie Kasari, PhD., Bryan King, MD, James McCracken, MD, Christopher McDougle, MD, Lawrence Scahill, MSN, PhD, Robert Schultz, PhD and Helen Tager-Flusberg, PhD, the input of the funding organizations and the families and children who participated. Dr. Handen received support from the National Institute for Aging (R01AG031110-03A1; 1 R01 AG051406-01), Autism Speaks, Roche and Eli Lilly. Dr. Mazefsky receives support from the National Institute of Child Health and Human Development (R01HD079512; K23HD060601). Drs. Gabriels, Pedersen, Wallace have no conflicts of interest.
Funding Information:
Conflict of interest Dr. Handen received support from the National Institute for Aging (R01AG031110-03A1; 1 R01 AG051406-01), Autism Speaks, Roche and Eli Lilly. Dr. Mazefsky receives support from the National Institute of Child Health and Human Development (R01HD079512; K23HD060601). Drs. Gabriels, Pedersen, Wallace have no conflicts of interest.
Publisher Copyright:
© 2018, Springer Science+Business Media, LLC, part of Springer Nature.
PY - 2018/11/1
Y1 - 2018/11/1
N2 - Limited information about self-injurious behavior (SIB) is known for children and adolescents with Autism Spectrum Disorder (ASD) who require intensive behavioral health interventions. We examined risk-factors for SIB in 302 individuals with ASD (ages 4–20) admitted to six specialized psychiatric inpatient units. Seventy-four percent were reported by a caregiver to display SIB, however, only 25% were observed to engage in daily SIB during hospitalization. Those exhibiting SIB across environments had significantly higher ratings on caregiver questionnaires of SIB severity. Tree-structured classification was used to develop and validate two predictive models, one indicating which inpatient youth with ASD are likely to have SIB and a second indicating which individuals with SIB at home are likely to continue in an inpatient setting.
AB - Limited information about self-injurious behavior (SIB) is known for children and adolescents with Autism Spectrum Disorder (ASD) who require intensive behavioral health interventions. We examined risk-factors for SIB in 302 individuals with ASD (ages 4–20) admitted to six specialized psychiatric inpatient units. Seventy-four percent were reported by a caregiver to display SIB, however, only 25% were observed to engage in daily SIB during hospitalization. Those exhibiting SIB across environments had significantly higher ratings on caregiver questionnaires of SIB severity. Tree-structured classification was used to develop and validate two predictive models, one indicating which inpatient youth with ASD are likely to have SIB and a second indicating which individuals with SIB at home are likely to continue in an inpatient setting.
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U2 - 10.1007/s10803-017-3460-2
DO - 10.1007/s10803-017-3460-2
M3 - Article
C2 - 29368233
AN - SCOPUS:85040904235
SN - 0162-3257
VL - 48
SP - 3678
EP - 3688
JO - Journal of Autism and Developmental Disorders
JF - Journal of Autism and Developmental Disorders
IS - 11
ER -