Robotic-Guided Bihippocampal and Biparahippocampal Depth Placement for Responsive Neurostimulation in Bitemporal Lobe Epilepsy

Pratik Rohatgi, Ryan J. Jafrani, Nicholas J. Brandmeir, Frank G. Gilliam, Tiffany Fisher, Michael Sather

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Background Patients with bitemporal lobe epilepsy are generally not considered for surgical resection. Fortunately, responsive neurostimulation provides another avenue for the management of this challenging disease process. In conjunction with our epileptologist, we consider responsive neurostimulation for patients who have clinical features of temporal lobe epilepsy without clear localization on imaging and stereoelectroencephalography. Methods Here we describe our technique for implanting a responsive neurostimulator (NeuroPace, NeuroPace Inc., Mountain View, California) with depth electrodes monitoring the hippocampus and parahippocampus using stereotactic robotic guidance (ROSA, Medtech SA, Montpeillier, France). Results We have used this technique with 5 patients without morbidity. Four of 5 patients have received clinical benefit (Engel classification I–III). Promisingly, long-term seizure monitoring with use of the NeuroPace system has suggested lateralizing information on 3 of these patients that was not apparent on previous invasive monitoring. Conclusions Robotically implanted responsive neurostimulation is a safe and effective treatment for bitemporal epilepsy and can possibly lead to valuable diagnostic information to guide future surgical management in patients who previously were not considered candidates for resective or ablative surgery.

Original languageEnglish (US)
Pages (from-to)181-189
Number of pages9
JournalWorld Neurosurgery
Volume111
DOIs
StatePublished - Mar 1 2018

Fingerprint

Robotics
Epilepsy
Temporal Lobe Epilepsy
Disease Management
France
Hippocampus
Electrodes
Seizures
Morbidity

All Science Journal Classification (ASJC) codes

  • Surgery
  • Clinical Neurology

Cite this

Rohatgi, Pratik ; Jafrani, Ryan J. ; Brandmeir, Nicholas J. ; Gilliam, Frank G. ; Fisher, Tiffany ; Sather, Michael. / Robotic-Guided Bihippocampal and Biparahippocampal Depth Placement for Responsive Neurostimulation in Bitemporal Lobe Epilepsy. In: World Neurosurgery. 2018 ; Vol. 111. pp. 181-189.
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abstract = "Background Patients with bitemporal lobe epilepsy are generally not considered for surgical resection. Fortunately, responsive neurostimulation provides another avenue for the management of this challenging disease process. In conjunction with our epileptologist, we consider responsive neurostimulation for patients who have clinical features of temporal lobe epilepsy without clear localization on imaging and stereoelectroencephalography. Methods Here we describe our technique for implanting a responsive neurostimulator (NeuroPace, NeuroPace Inc., Mountain View, California) with depth electrodes monitoring the hippocampus and parahippocampus using stereotactic robotic guidance (ROSA, Medtech SA, Montpeillier, France). Results We have used this technique with 5 patients without morbidity. Four of 5 patients have received clinical benefit (Engel classification I–III). Promisingly, long-term seizure monitoring with use of the NeuroPace system has suggested lateralizing information on 3 of these patients that was not apparent on previous invasive monitoring. Conclusions Robotically implanted responsive neurostimulation is a safe and effective treatment for bitemporal epilepsy and can possibly lead to valuable diagnostic information to guide future surgical management in patients who previously were not considered candidates for resective or ablative surgery.",
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Robotic-Guided Bihippocampal and Biparahippocampal Depth Placement for Responsive Neurostimulation in Bitemporal Lobe Epilepsy. / Rohatgi, Pratik; Jafrani, Ryan J.; Brandmeir, Nicholas J.; Gilliam, Frank G.; Fisher, Tiffany; Sather, Michael.

In: World Neurosurgery, Vol. 111, 01.03.2018, p. 181-189.

Research output: Contribution to journalArticle

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