Role for migratory wild birds in the global spread of avian influenza H5N8

The Global Consortium for H5N8 and Related Influenza Viruses

Research output: Contribution to journalArticle

136 Citations (Scopus)

Abstract

Avian influenza viruses affect both poultry production and public health. A subtype H5N8 (clade 2.3.4.4) virus, following an outbreak in poultry in South Korea in January 2014, rapidly spread worldwide in 2014-2015. Our analysis of H5N8 viral sequences, epidemiological investigations, waterfowl migration, and poultry trade showed that long-distance migratory birds can play a major role in the global spread of avian influenza viruses. Further, we found that the hemagglutinin of clade 2.3.4.4 virus was remarkably promiscuous, creating reassortants with multiple neuraminidase subtypes. Improving our understanding of the circumpolar circulation of avian influenza viruses in migratory waterfowl will help to provide early warning of threats from avian influenza to poultry, and potentially human, health.

Original languageEnglish (US)
Pages (from-to)213-217
Number of pages5
JournalScience
Volume354
Issue number6309
DOIs
StatePublished - Oct 14 2016

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Influenza in Birds
Poultry
Birds
Orthomyxoviridae
Viruses
Republic of Korea
Hemagglutinins
Neuraminidase
Disease Outbreaks
Public Health
Health

All Science Journal Classification (ASJC) codes

  • General

Cite this

The Global Consortium for H5N8 and Related Influenza Viruses (2016). Role for migratory wild birds in the global spread of avian influenza H5N8. Science, 354(6309), 213-217. https://doi.org/10.1126/science.aaf8852
The Global Consortium for H5N8 and Related Influenza Viruses. / Role for migratory wild birds in the global spread of avian influenza H5N8. In: Science. 2016 ; Vol. 354, No. 6309. pp. 213-217.
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abstract = "Avian influenza viruses affect both poultry production and public health. A subtype H5N8 (clade 2.3.4.4) virus, following an outbreak in poultry in South Korea in January 2014, rapidly spread worldwide in 2014-2015. Our analysis of H5N8 viral sequences, epidemiological investigations, waterfowl migration, and poultry trade showed that long-distance migratory birds can play a major role in the global spread of avian influenza viruses. Further, we found that the hemagglutinin of clade 2.3.4.4 virus was remarkably promiscuous, creating reassortants with multiple neuraminidase subtypes. Improving our understanding of the circumpolar circulation of avian influenza viruses in migratory waterfowl will help to provide early warning of threats from avian influenza to poultry, and potentially human, health.",
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The Global Consortium for H5N8 and Related Influenza Viruses 2016, 'Role for migratory wild birds in the global spread of avian influenza H5N8', Science, vol. 354, no. 6309, pp. 213-217. https://doi.org/10.1126/science.aaf8852

Role for migratory wild birds in the global spread of avian influenza H5N8. / The Global Consortium for H5N8 and Related Influenza Viruses.

In: Science, Vol. 354, No. 6309, 14.10.2016, p. 213-217.

Research output: Contribution to journalArticle

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AU - The Global Consortium for H5N8 and Related Influenza Viruses

AU - Lycett, Samantha J.

AU - Bodewes, Rogier

AU - Pohlmann, Anne

AU - Banks, Jill

AU - Bányai, Krisztián

AU - Boni, Maciej F.

AU - Bouwstra, Ruth

AU - Breed, Andrew C.

AU - Brown, Ian H.

AU - Chen, Hualan

AU - Dán, Ádám

AU - DeLiberto, Thomas J.

AU - Diep, Nguyen

AU - Gilbert, Marius

AU - Hill, Sarah

AU - Ip, Hon S.

AU - Ke, Chang Wen

AU - Kida, Hiroshi

AU - Killian, Mary Lea

AU - Koopmans, Marion P.

AU - Kwon, Jung Hoon

AU - Lee, Dong Hun

AU - Lee, Youn Jeong

AU - Lu, Lu

AU - Monne, Isabella

AU - Pasick, John

AU - Pybus, Oliver G.

AU - Rambaut, Andrew

AU - Robinson, Timothy P.

AU - Sakoda, Yoshihiro

AU - Zohari, Siamak

AU - Song, Chang Seon

AU - Swayne, David E.

AU - Torchetti, Mia Kim

AU - Tsai, Hsiang Jung

AU - Fouchier, Ron A.M.

AU - Beer, Martin

AU - Woolhouse, Mark

AU - Kuiken, Thijs

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The Global Consortium for H5N8 and Related Influenza Viruses. Role for migratory wild birds in the global spread of avian influenza H5N8. Science. 2016 Oct 14;354(6309):213-217. https://doi.org/10.1126/science.aaf8852