Safety Assessment of Alkyl PEG Ethers as Used in Cosmetics

Monice M. Fiume, Bart Heldreth, Wilma F. Bergfeld, Donald V. Belsito, Ronald A. Hill, Curtis D. Klaassen, Daniel Liebler, James Marks, Ronald C. Shank, Thomas J. Slaga, Paul W. Snyder, F. Alan Andersen

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

The CIR Expert Panel assessed the safety of Alkyl PEG Ethers as used in cosmetics. These ingredients primarily function in cosmetics as surfactants, and some have additional functions as skin-conditioning agents, fragrance ingredients, and emulsion stabilizers. The Panel reviewed available relevant animal and clinical data, as well as information from previous CIR reports; when data were not available for individual ingredients, the Panel extrapolated from the existing data to support safety. The Panel concluded that the Alkyl PEG ethers are safe as used when formulated to be nonirritating, and the same applies to future alkyl PEG ether cosmetic ingredients that vary from those ingredients recited herein only by the number of ethylene glycol repeat units.

Original languageEnglish (US)
Pages (from-to)169S-244S
JournalInternational journal of toxicology
Volume31
DOIs
StatePublished - Jan 1 2012

Fingerprint

Ethers
Cosmetics
Polyethylene glycols
Safety
Fragrances
Stabilizers (agents)
Ethylene Glycol
Emulsions
Surface-Active Agents
Ether
Skin
Animals

All Science Journal Classification (ASJC) codes

  • Toxicology

Cite this

Fiume, M. M., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... Andersen, F. A. (2012). Safety Assessment of Alkyl PEG Ethers as Used in Cosmetics. International journal of toxicology, 31, 169S-244S. https://doi.org/10.1177/1091581812444141
Fiume, Monice M. ; Heldreth, Bart ; Bergfeld, Wilma F. ; Belsito, Donald V. ; Hill, Ronald A. ; Klaassen, Curtis D. ; Liebler, Daniel ; Marks, James ; Shank, Ronald C. ; Slaga, Thomas J. ; Snyder, Paul W. ; Andersen, F. Alan. / Safety Assessment of Alkyl PEG Ethers as Used in Cosmetics. In: International journal of toxicology. 2012 ; Vol. 31. pp. 169S-244S.
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Fiume, MM, Heldreth, B, Bergfeld, WF, Belsito, DV, Hill, RA, Klaassen, CD, Liebler, D, Marks, J, Shank, RC, Slaga, TJ, Snyder, PW & Andersen, FA 2012, 'Safety Assessment of Alkyl PEG Ethers as Used in Cosmetics', International journal of toxicology, vol. 31, pp. 169S-244S. https://doi.org/10.1177/1091581812444141

Safety Assessment of Alkyl PEG Ethers as Used in Cosmetics. / Fiume, Monice M.; Heldreth, Bart; Bergfeld, Wilma F.; Belsito, Donald V.; Hill, Ronald A.; Klaassen, Curtis D.; Liebler, Daniel; Marks, James; Shank, Ronald C.; Slaga, Thomas J.; Snyder, Paul W.; Andersen, F. Alan.

In: International journal of toxicology, Vol. 31, 01.01.2012, p. 169S-244S.

Research output: Contribution to journalArticle

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Fiume MM, Heldreth B, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD et al. Safety Assessment of Alkyl PEG Ethers as Used in Cosmetics. International journal of toxicology. 2012 Jan 1;31:169S-244S. https://doi.org/10.1177/1091581812444141