Safety Assessment of Animal- and Plant-Derived Amino Acids as Used in Cosmetics

Christina Burnett, Bart Heldreth, Wilma F. Bergfeld, Donald V. Belsito, Ronald A. Hill, Curtis D. Klaassen, Daniel C. Liebler, James G. Marks, Ronald C. Shank, Thomas J. Slaga, Paul W. Snyder, F. Alan Andersen

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


The Cosmetic Ingredient Review Expert Panel (Panel) reviewed the safety of animal- and plant-derived amino acid mixtures, which function as skin and hair conditioning agents. The safety of α-amino acids as direct food additives has been well established, based on extensive research through acute and chronic dietary exposures and the Panel previously has reviewed the safety of individual α-amino acids in cosmetics. The Panel focused its review on dermal irritation and sensitization data relevant to the use of these ingredients in topical cosmetics. The Panel concluded that these 21 ingredients are safe in the present practices of use and concentration as used in cosmetics.

Original languageEnglish (US)
Pages (from-to)5S-12S
JournalInternational journal of toxicology
StatePublished - Nov 2014

All Science Journal Classification (ASJC) codes

  • Toxicology


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