Safety Assessment of PEGs Cocamine and Related Ingredients as Used in Cosmetics

Ivan Boyer, Christina L. Burnett, Wilma F. Bergfeld, Donald V. Belsito, Ronald A. Hill, Curtis D. Klaassen, Daniel C. Liebler, James Marks, Ronald C. Shank, Thomas J. Slaga, Paul W. Snyder, Lillian J. Gill, Bart Heldreth

Research output: Contribution to journalArticle

Abstract

The Cosmetic Ingredient Review Expert Panel assessed the safety of 47 polyethylene glycols (PEGs) cocamine and related ingredients, which are reported to function mostly as surfactants and antistatic agents. The Panel reviewed the relevant data and developed a framework to satisfy previously identified data deficiencies for this group of materials as well as extend the scope of related materials covered by the analysis. The irritation potential of these ingredients is consistent with the surface active properties that are characteristic of surfactants. The Panel concluded that the PEGs cocamine and related ingredients were safe as ingredients in cosmetic formulations in the current practices of use and concentration when formulated to be nonirritating.

Original languageEnglish (US)
Pages (from-to)10S-60S
JournalInternational journal of toxicology
Volume37
Issue number2_suppl
DOIs
StatePublished - Sep 1 2018

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Cosmetics
Surface-Active Agents
Antistatic Agents
Safety
Surface Properties

All Science Journal Classification (ASJC) codes

  • Toxicology

Cite this

Boyer, I., Burnett, C. L., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... Heldreth, B. (2018). Safety Assessment of PEGs Cocamine and Related Ingredients as Used in Cosmetics. International journal of toxicology, 37(2_suppl), 10S-60S. https://doi.org/10.1177/1091581818794417
Boyer, Ivan ; Burnett, Christina L. ; Bergfeld, Wilma F. ; Belsito, Donald V. ; Hill, Ronald A. ; Klaassen, Curtis D. ; Liebler, Daniel C. ; Marks, James ; Shank, Ronald C. ; Slaga, Thomas J. ; Snyder, Paul W. ; Gill, Lillian J. ; Heldreth, Bart. / Safety Assessment of PEGs Cocamine and Related Ingredients as Used in Cosmetics. In: International journal of toxicology. 2018 ; Vol. 37, No. 2_suppl. pp. 10S-60S.
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Boyer, I, Burnett, CL, Bergfeld, WF, Belsito, DV, Hill, RA, Klaassen, CD, Liebler, DC, Marks, J, Shank, RC, Slaga, TJ, Snyder, PW, Gill, LJ & Heldreth, B 2018, 'Safety Assessment of PEGs Cocamine and Related Ingredients as Used in Cosmetics', International journal of toxicology, vol. 37, no. 2_suppl, pp. 10S-60S. https://doi.org/10.1177/1091581818794417

Safety Assessment of PEGs Cocamine and Related Ingredients as Used in Cosmetics. / Boyer, Ivan; Burnett, Christina L.; Bergfeld, Wilma F.; Belsito, Donald V.; Hill, Ronald A.; Klaassen, Curtis D.; Liebler, Daniel C.; Marks, James; Shank, Ronald C.; Slaga, Thomas J.; Snyder, Paul W.; Gill, Lillian J.; Heldreth, Bart.

In: International journal of toxicology, Vol. 37, No. 2_suppl, 01.09.2018, p. 10S-60S.

Research output: Contribution to journalArticle

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Boyer I, Burnett CL, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD et al. Safety Assessment of PEGs Cocamine and Related Ingredients as Used in Cosmetics. International journal of toxicology. 2018 Sep 1;37(2_suppl):10S-60S. https://doi.org/10.1177/1091581818794417