Safety Assessment of Pentaerythrityl Tetraesters as Used in Cosmetics

Lillian C. Becker, Wilma F. Bergfeld, Donald V. Belsito, Ronald A. Hill, Curtis D. Klaassen, Daniel C. Liebler, James Marks, Ronald C. Shank, Thomas J. Slaga, Paul W. Snyder, F. Alan Andersen

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The Cosmetic Ingredient Review (CIR) Expert Panel (Panel) reviewed the safety of 16 pentaerythrityl tetraester compounds as used in cosmetics. These ingredients mostly function as hair-conditioning agents, skin-conditioning agents—miscellaneous and binders, skin-conditioning agents–occlusive, viscosity-increasing agents–nonaqueous, and skin-conditioning agents—emollient. The Panel reviewed the available animal and human data related to these ingredients and previous safety assessments of the fatty acid moieties. The Panel concluded that pentaerythrityl tetraisostearate and the other pentaerythrityl tetraester compounds were safe in the practices of use and concentration as given in this safety assessment.

Original languageEnglish (US)
Pages (from-to)99S-112S
JournalInternational journal of toxicology
Volume34
DOIs
StatePublished - Jan 1 2015

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Cosmetics
Skin
Safety
Viscosity
Hair
Binders
Animals
Fatty Acids

All Science Journal Classification (ASJC) codes

  • Toxicology

Cite this

Becker, L. C., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... Andersen, F. A. (2015). Safety Assessment of Pentaerythrityl Tetraesters as Used in Cosmetics. International journal of toxicology, 34, 99S-112S. https://doi.org/10.1177/1091581815596731
Becker, Lillian C. ; Bergfeld, Wilma F. ; Belsito, Donald V. ; Hill, Ronald A. ; Klaassen, Curtis D. ; Liebler, Daniel C. ; Marks, James ; Shank, Ronald C. ; Slaga, Thomas J. ; Snyder, Paul W. ; Andersen, F. Alan. / Safety Assessment of Pentaerythrityl Tetraesters as Used in Cosmetics. In: International journal of toxicology. 2015 ; Vol. 34. pp. 99S-112S.
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Becker, LC, Bergfeld, WF, Belsito, DV, Hill, RA, Klaassen, CD, Liebler, DC, Marks, J, Shank, RC, Slaga, TJ, Snyder, PW & Andersen, FA 2015, 'Safety Assessment of Pentaerythrityl Tetraesters as Used in Cosmetics', International journal of toxicology, vol. 34, pp. 99S-112S. https://doi.org/10.1177/1091581815596731

Safety Assessment of Pentaerythrityl Tetraesters as Used in Cosmetics. / Becker, Lillian C.; Bergfeld, Wilma F.; Belsito, Donald V.; Hill, Ronald A.; Klaassen, Curtis D.; Liebler, Daniel C.; Marks, James; Shank, Ronald C.; Slaga, Thomas J.; Snyder, Paul W.; Andersen, F. Alan.

In: International journal of toxicology, Vol. 34, 01.01.2015, p. 99S-112S.

Research output: Contribution to journalArticle

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Becker LC, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC et al. Safety Assessment of Pentaerythrityl Tetraesters as Used in Cosmetics. International journal of toxicology. 2015 Jan 1;34:99S-112S. https://doi.org/10.1177/1091581815596731