Safety Assessment of Sorbitan Esters as Used in Cosmetics

Monice M. Fiume, Wilma F. Bergfeld, Donald V. Belsito, Ronald A. Hill, Curtis D. Klaassen, Daniel C. Liebler, James Marks, Ronald C. Shank, Thomas J. Slaga, Paul W. Snyder, Lillian J. Gill, Bart Heldreth

Research output: Contribution to journalArticle

Abstract

The Cosmetic Ingredient Review Expert Panel (Panel) assessed the safety of 20 sorbitan esters; this report included sorbitan esters that were reviewed in 1985 and 2002, as well as 3 previously unreviewed sorbitan esters (sorbitan undecylenate, sorbitan sesquicaprylate, and sorbitan palmate). Most of the sorbitan esters are reported to function in cosmetics as surfactant-emulsifying agents. The Panel reviewed the data from previous sorbitan ester reports, as well as additional data included in this report, to determine the safety of these ingredients. The Panel concluded that the sorbitan esters included in this safety assessment are safe in cosmetics in the present practices of use and concentration.

Original languageEnglish (US)
Pages (from-to)60S-80S
JournalInternational journal of toxicology
Volume38
Issue number2_suppl
DOIs
StatePublished - Sep 1 2019

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Cosmetics
Esters
Safety
Emulsifying Agents
Surface-Active Agents

All Science Journal Classification (ASJC) codes

  • Toxicology

Cite this

Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... Heldreth, B. (2019). Safety Assessment of Sorbitan Esters as Used in Cosmetics. International journal of toxicology, 38(2_suppl), 60S-80S. https://doi.org/10.1177/1091581819871877
Fiume, Monice M. ; Bergfeld, Wilma F. ; Belsito, Donald V. ; Hill, Ronald A. ; Klaassen, Curtis D. ; Liebler, Daniel C. ; Marks, James ; Shank, Ronald C. ; Slaga, Thomas J. ; Snyder, Paul W. ; Gill, Lillian J. ; Heldreth, Bart. / Safety Assessment of Sorbitan Esters as Used in Cosmetics. In: International journal of toxicology. 2019 ; Vol. 38, No. 2_suppl. pp. 60S-80S.
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Fiume, MM, Bergfeld, WF, Belsito, DV, Hill, RA, Klaassen, CD, Liebler, DC, Marks, J, Shank, RC, Slaga, TJ, Snyder, PW, Gill, LJ & Heldreth, B 2019, 'Safety Assessment of Sorbitan Esters as Used in Cosmetics', International journal of toxicology, vol. 38, no. 2_suppl, pp. 60S-80S. https://doi.org/10.1177/1091581819871877

Safety Assessment of Sorbitan Esters as Used in Cosmetics. / Fiume, Monice M.; Bergfeld, Wilma F.; Belsito, Donald V.; Hill, Ronald A.; Klaassen, Curtis D.; Liebler, Daniel C.; Marks, James; Shank, Ronald C.; Slaga, Thomas J.; Snyder, Paul W.; Gill, Lillian J.; Heldreth, Bart.

In: International journal of toxicology, Vol. 38, No. 2_suppl, 01.09.2019, p. 60S-80S.

Research output: Contribution to journalArticle

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Fiume MM, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC et al. Safety Assessment of Sorbitan Esters as Used in Cosmetics. International journal of toxicology. 2019 Sep 1;38(2_suppl):60S-80S. https://doi.org/10.1177/1091581819871877