Abstract
The Cosmetic Ingredient Review (CIR) Expert Panel (Panel) assessed the safety of 14 tocopherols and tocotrienols and concluded these ingredients are safe as used in cosmetics. The tocopherols are reported to function in cosmetics as antioxidants or skin-conditioning agents; in contrast, tocotrienols are not reported to function as an antioxidants in cosmetics but as a light stabilizer, oral care agent, or skin-conditioning agent. The Panel reviewed the new and existing animal and clinical data to determine the safety of these ingredients and found it appropriate to extrapolate the existing information to conclude on the safety of all the tocopherols and tocotrienols.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 61S-94S |
| Journal | International journal of toxicology |
| Volume | 37 |
| Issue number | 2_suppl |
| DOIs | |
| State | Published - Sep 1 2018 |
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All Science Journal Classification (ASJC) codes
- Toxicology
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Safety Assessment of Tocopherols and Tocotrienols as Used in Cosmetics. / Fiume, Monice M.; Bergfeld, Wilma F.; Belsito, Donald V.; Hill, Ronald A.; Klaassen, Curtis D.; Liebler, Daniel C.; Marks, James; Shank, Ronald C.; Slaga, Thomas J.; Snyder, Paul W.; Andersen, F. Alan; Heldreth, Bart.
In: International journal of toxicology, Vol. 37, No. 2_suppl, 01.09.2018, p. 61S-94S.Research output: Contribution to journal › Article
TY - JOUR
T1 - Safety Assessment of Tocopherols and Tocotrienols as Used in Cosmetics
AU - Fiume, Monice M.
AU - Bergfeld, Wilma F.
AU - Belsito, Donald V.
AU - Hill, Ronald A.
AU - Klaassen, Curtis D.
AU - Liebler, Daniel C.
AU - Marks, James
AU - Shank, Ronald C.
AU - Slaga, Thomas J.
AU - Snyder, Paul W.
AU - Andersen, F. Alan
AU - Heldreth, Bart
PY - 2018/9/1
Y1 - 2018/9/1
N2 - The Cosmetic Ingredient Review (CIR) Expert Panel (Panel) assessed the safety of 14 tocopherols and tocotrienols and concluded these ingredients are safe as used in cosmetics. The tocopherols are reported to function in cosmetics as antioxidants or skin-conditioning agents; in contrast, tocotrienols are not reported to function as an antioxidants in cosmetics but as a light stabilizer, oral care agent, or skin-conditioning agent. The Panel reviewed the new and existing animal and clinical data to determine the safety of these ingredients and found it appropriate to extrapolate the existing information to conclude on the safety of all the tocopherols and tocotrienols.
AB - The Cosmetic Ingredient Review (CIR) Expert Panel (Panel) assessed the safety of 14 tocopherols and tocotrienols and concluded these ingredients are safe as used in cosmetics. The tocopherols are reported to function in cosmetics as antioxidants or skin-conditioning agents; in contrast, tocotrienols are not reported to function as an antioxidants in cosmetics but as a light stabilizer, oral care agent, or skin-conditioning agent. The Panel reviewed the new and existing animal and clinical data to determine the safety of these ingredients and found it appropriate to extrapolate the existing information to conclude on the safety of all the tocopherols and tocotrienols.
UR - http://www.scopus.com/inward/record.url?scp=85053800834&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85053800834&partnerID=8YFLogxK
U2 - 10.1177/1091581818794455
DO - 10.1177/1091581818794455
M3 - Article
C2 - 30235959
AN - SCOPUS:85053800834
VL - 37
SP - 61S-94S
JO - International Journal of Toxicology
JF - International Journal of Toxicology
SN - 1091-5818
IS - 2_suppl
ER -