Micafungin is used off-label in the United States to treat invasive candidiasis in neonates. We used an established pharmacokinetic model to determine micafungin exposures for 46 courses in 39 hospitalized infants. In this small cohort of infants, micafungin exposure was not associated with laboratory markers of liver toxicity, death or failure of microbiologic clearance.
All Science Journal Classification (ASJC) codes
- Pediatrics, Perinatology, and Child Health
- Microbiology (medical)
- Infectious Diseases