Safety issues of maternal drug therapy during breastfeeding

Cheston Berlin, Ian Paul, E. S. Vesell

Research output: Contribution to journalComment/debate

21 Citations (Scopus)

Abstract

Two goals when counseling breastfeeding mothers taking medication are protecting the infant from adverse events and permitting necessary maternal therapy. Madadi et al. report a case-control study of neonatal and maternal opioid toxicity after codeine administration. Therapeutic considerations in counseling breastfeeding mothers include susceptibility to drug toxicity of the very young and/or premature infant, significant interindividual variations in drug response, the dose-response relationship with respect to drug toxicity, and the role of pharmacogenetics in both the mother and the infant. These host factors may combine in a particular patient to act synergistically to produce an adverse reaction.

Original languageEnglish (US)
Pages (from-to)20-22
Number of pages3
JournalClinical pharmacology and therapeutics
Volume85
Issue number1
DOIs
StatePublished - Jan 1 2009

Fingerprint

Breast Feeding
Mothers
Safety
Drug Therapy
Drug-Related Side Effects and Adverse Reactions
Drug Dose Response Relationship
Counseling
Codeine
Pharmacogenetics
Premature Infants
Opioid Analgesics
Case-Control Studies
Therapeutics

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Pharmacology (medical)

Cite this

Berlin, Cheston ; Paul, Ian ; Vesell, E. S. / Safety issues of maternal drug therapy during breastfeeding. In: Clinical pharmacology and therapeutics. 2009 ; Vol. 85, No. 1. pp. 20-22.
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Safety issues of maternal drug therapy during breastfeeding. / Berlin, Cheston; Paul, Ian; Vesell, E. S.

In: Clinical pharmacology and therapeutics, Vol. 85, No. 1, 01.01.2009, p. 20-22.

Research output: Contribution to journalComment/debate

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