Scleromyxedema presenting with neurologic symptoms: A case report and review of the literature

Kathleen Marshal, Stacy A. Klepeiss, Michael D. Ioffreda, Klaus F. Helm

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Scleromyxedema is a rare variant of lichen myxedematosus. In addition to cutaneous manifestations, scleromyxedema often presents with systemic manifestations, including dysphagia, proximal muscle weakness, central nervous system disturbances, encephalopathy, and restrictive lung disease. It is almost always associated with paraproteinemia, usually IgG with γ light chains. We review the literature on scleromyxedema associated with neurologic symptoms and present a case of a 49-year-old woman with encephalopathy attributable to scleromyxedema.

Original languageEnglish (US)
Pages (from-to)137-140
Number of pages4
JournalCutis
Volume85
Issue number3
StatePublished - Mar 1 2010

All Science Journal Classification (ASJC) codes

  • Dermatology

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