Seeing the forest for the trees: Annotating small RNA producing genes in plants

Ceyda Coruh, Saima Shahid, Michael J. Axtell

Research output: Contribution to journalReview articlepeer-review

22 Scopus citations

Abstract

A key goal in genomics is the complete annotation of the expressed regions of the genome. In plants, substantial portions of the genome make regulatory small RNAs produced by Dicer-Like (DCL) proteins and utilized by Argonaute (AGO) proteins. These include miRNAs and various types of endogenous siRNAs. Small RNA-seq, enabled by cheap and fast DNA sequencing, has produced an enormous volume of data on plant miRNA and siRNA expression in recent years. In this review, we discuss recent progress in using small RNA-seq data to produce stable and reliable annotations of miRNA and siRNA genes in plants. In addition, we highlight key goals for the future of small RNA gene annotation in plants.

Original languageEnglish (US)
Pages (from-to)87-95
Number of pages9
JournalCurrent Opinion in Plant Biology
Volume18
Issue number1
DOIs
StatePublished - Apr 2014

All Science Journal Classification (ASJC) codes

  • Plant Science

Fingerprint Dive into the research topics of 'Seeing the forest for the trees: Annotating small RNA producing genes in plants'. Together they form a unique fingerprint.

Cite this