This paper presents the results of the first phase of an experimental research program on simulated seismic performance of structural silicone glazed (SSG) curtain wall systems. Full-scale, two-side SSG mockups made up of three side-by-side glass panels were tested under cyclic racking displacements to determine serviceability and ultimate behavior responses. Variables were glass type (annealed and fully tempered) and panel configuration (monolithic, laminated, and insulating glass). In the experiments carried out, damage states such as gasket deformation/pullout, sealant failure (e.g., adhesion/cohesion, etc.), glass cracking glass and fallout were identified and their corresponding drift levels were determined. The extent of damage to silicone sealant was determined through air leakage tests.