Selective neuronal vulnerability to hypoxia in vitro

Peter G. Aitken, Steven Schiff

Research output: Contribution to journalArticlepeer-review

52 Scopus citations


Hippocampal slices were subjected to a sequence of hypoxic periods of progressively increasing duration. In all slices, synaptic transmission returned during reoxygenation in the fascia dentata, but not in CA1. Thus, the relative vulnerability of CA1 and the fascia dentata to ischemia in situ can be replicated by a purely hypoxic insult in vitro.

Original languageEnglish (US)
Pages (from-to)92-96
Number of pages5
JournalNeuroscience letters
Issue number1
StatePublished - Jun 6 1986

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)


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