Sepsis and inflammatory insults downregulate IGFBP-5, but not IGFBP-4, in skeletal muscle via a TNF-dependent mechanism

Medicine & Life Sciences

• Insulin-Like Growth Factor Binding Protein 5 100%
• Insulin-Like Growth Factor Binding Protein 4 99%
• Sepsis 52%
• Skeletal Muscle 51%
• Down-Regulation 45%
• Muscles 33%
• Messenger RNA 28%
• Insulin-Like Growth Factor I 25%
• Growth Hormone 14%
• Hindlimb Suspension 13%
• Insulin-Like Growth Factor Binding Protein 3 6%
• Muscular Atrophy 5%
• Myoblasts 5%
• Glucocorticoid Receptors 5%