Sequencing the genome of Marssonina brunnea reveals fungus-poplar co-evolution

Sheng Zhu, You Zhi Cao, Cong Jiang, Bi Yue Tan, Zhong Wang, Sisi Feng, Liang Zhang, Xiao Hua Su, Brona Brejova, Tomas Vinar, Meng Xu, Ming Xiu Wang, Shou Gong Zhang, Min Ren Huang, Rongling Wu, Yan Zhou

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Background: The fungus Marssonina brunnea is a causal pathogen of Marssonina leaf spot that devastates poplar plantations by defoliating susceptible trees before normal fall leaf drop.Results: We sequence the genome of M. brunnea with a size of 52 Mb assembled into 89 scaffolds, representing the first sequenced Dermateaceae genome. By inoculating this fungus onto a poplar hybrid clone, we investigate how M. brunnea interacts and co-evolves with its host to colonize poplar leaves. While a handful of virulence genes in M. brunnea, mostly from the LysM family, are detected to up-regulate during infection, the poplar down-regulates its resistance genes, such as nucleotide binding site domains and leucine rich repeats, in response to infection. From 10,027 predicted proteins of M. brunnea in a comparison with those from poplar, we identify four poplar transferases that stimulate the host to resist M. brunnea. These transferas-encoding genes may have driven the co-evolution of M. brunnea and Populus during the process of infection and anti-infection.Conclusions: Our results from the draft sequence of the M. brunnea genome provide evidence for genome-genome interactions that play an important role in poplar-pathogen co-evolution. This knowledge could help to design effective strategies for controlling Marssonina leaf spot in poplar.

Original languageEnglish (US)
Article number382
JournalBMC genomics
Volume13
Issue number1
DOIs
StatePublished - Aug 9 2012

Fingerprint

Fungi
Genome
Infection
Genes
Populus
Transferases
Leucine
Virulence
Up-Regulation
Down-Regulation
Nucleotides
Clone Cells
Binding Sites
Proteins

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Genetics

Cite this

Zhu, S., Cao, Y. Z., Jiang, C., Tan, B. Y., Wang, Z., Feng, S., ... Zhou, Y. (2012). Sequencing the genome of Marssonina brunnea reveals fungus-poplar co-evolution. BMC genomics, 13(1), [382]. https://doi.org/10.1186/1471-2164-13-382
Zhu, Sheng ; Cao, You Zhi ; Jiang, Cong ; Tan, Bi Yue ; Wang, Zhong ; Feng, Sisi ; Zhang, Liang ; Su, Xiao Hua ; Brejova, Brona ; Vinar, Tomas ; Xu, Meng ; Wang, Ming Xiu ; Zhang, Shou Gong ; Huang, Min Ren ; Wu, Rongling ; Zhou, Yan. / Sequencing the genome of Marssonina brunnea reveals fungus-poplar co-evolution. In: BMC genomics. 2012 ; Vol. 13, No. 1.
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abstract = "Background: The fungus Marssonina brunnea is a causal pathogen of Marssonina leaf spot that devastates poplar plantations by defoliating susceptible trees before normal fall leaf drop.Results: We sequence the genome of M. brunnea with a size of 52 Mb assembled into 89 scaffolds, representing the first sequenced Dermateaceae genome. By inoculating this fungus onto a poplar hybrid clone, we investigate how M. brunnea interacts and co-evolves with its host to colonize poplar leaves. While a handful of virulence genes in M. brunnea, mostly from the LysM family, are detected to up-regulate during infection, the poplar down-regulates its resistance genes, such as nucleotide binding site domains and leucine rich repeats, in response to infection. From 10,027 predicted proteins of M. brunnea in a comparison with those from poplar, we identify four poplar transferases that stimulate the host to resist M. brunnea. These transferas-encoding genes may have driven the co-evolution of M. brunnea and Populus during the process of infection and anti-infection.Conclusions: Our results from the draft sequence of the M. brunnea genome provide evidence for genome-genome interactions that play an important role in poplar-pathogen co-evolution. This knowledge could help to design effective strategies for controlling Marssonina leaf spot in poplar.",
author = "Sheng Zhu and Cao, {You Zhi} and Cong Jiang and Tan, {Bi Yue} and Zhong Wang and Sisi Feng and Liang Zhang and Su, {Xiao Hua} and Brona Brejova and Tomas Vinar and Meng Xu and Wang, {Ming Xiu} and Zhang, {Shou Gong} and Huang, {Min Ren} and Rongling Wu and Yan Zhou",
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Zhu, S, Cao, YZ, Jiang, C, Tan, BY, Wang, Z, Feng, S, Zhang, L, Su, XH, Brejova, B, Vinar, T, Xu, M, Wang, MX, Zhang, SG, Huang, MR, Wu, R & Zhou, Y 2012, 'Sequencing the genome of Marssonina brunnea reveals fungus-poplar co-evolution', BMC genomics, vol. 13, no. 1, 382. https://doi.org/10.1186/1471-2164-13-382

Sequencing the genome of Marssonina brunnea reveals fungus-poplar co-evolution. / Zhu, Sheng; Cao, You Zhi; Jiang, Cong; Tan, Bi Yue; Wang, Zhong; Feng, Sisi; Zhang, Liang; Su, Xiao Hua; Brejova, Brona; Vinar, Tomas; Xu, Meng; Wang, Ming Xiu; Zhang, Shou Gong; Huang, Min Ren; Wu, Rongling; Zhou, Yan.

In: BMC genomics, Vol. 13, No. 1, 382, 09.08.2012.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Sequencing the genome of Marssonina brunnea reveals fungus-poplar co-evolution

AU - Zhu, Sheng

AU - Cao, You Zhi

AU - Jiang, Cong

AU - Tan, Bi Yue

AU - Wang, Zhong

AU - Feng, Sisi

AU - Zhang, Liang

AU - Su, Xiao Hua

AU - Brejova, Brona

AU - Vinar, Tomas

AU - Xu, Meng

AU - Wang, Ming Xiu

AU - Zhang, Shou Gong

AU - Huang, Min Ren

AU - Wu, Rongling

AU - Zhou, Yan

PY - 2012/8/9

Y1 - 2012/8/9

N2 - Background: The fungus Marssonina brunnea is a causal pathogen of Marssonina leaf spot that devastates poplar plantations by defoliating susceptible trees before normal fall leaf drop.Results: We sequence the genome of M. brunnea with a size of 52 Mb assembled into 89 scaffolds, representing the first sequenced Dermateaceae genome. By inoculating this fungus onto a poplar hybrid clone, we investigate how M. brunnea interacts and co-evolves with its host to colonize poplar leaves. While a handful of virulence genes in M. brunnea, mostly from the LysM family, are detected to up-regulate during infection, the poplar down-regulates its resistance genes, such as nucleotide binding site domains and leucine rich repeats, in response to infection. From 10,027 predicted proteins of M. brunnea in a comparison with those from poplar, we identify four poplar transferases that stimulate the host to resist M. brunnea. These transferas-encoding genes may have driven the co-evolution of M. brunnea and Populus during the process of infection and anti-infection.Conclusions: Our results from the draft sequence of the M. brunnea genome provide evidence for genome-genome interactions that play an important role in poplar-pathogen co-evolution. This knowledge could help to design effective strategies for controlling Marssonina leaf spot in poplar.

AB - Background: The fungus Marssonina brunnea is a causal pathogen of Marssonina leaf spot that devastates poplar plantations by defoliating susceptible trees before normal fall leaf drop.Results: We sequence the genome of M. brunnea with a size of 52 Mb assembled into 89 scaffolds, representing the first sequenced Dermateaceae genome. By inoculating this fungus onto a poplar hybrid clone, we investigate how M. brunnea interacts and co-evolves with its host to colonize poplar leaves. While a handful of virulence genes in M. brunnea, mostly from the LysM family, are detected to up-regulate during infection, the poplar down-regulates its resistance genes, such as nucleotide binding site domains and leucine rich repeats, in response to infection. From 10,027 predicted proteins of M. brunnea in a comparison with those from poplar, we identify four poplar transferases that stimulate the host to resist M. brunnea. These transferas-encoding genes may have driven the co-evolution of M. brunnea and Populus during the process of infection and anti-infection.Conclusions: Our results from the draft sequence of the M. brunnea genome provide evidence for genome-genome interactions that play an important role in poplar-pathogen co-evolution. This knowledge could help to design effective strategies for controlling Marssonina leaf spot in poplar.

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